{
  "abstract": "目的先天性巨大中耳胆脂瘤合并中耳畸形由于病变位置隐匿、早期症状不典型，易因误诊而延误最佳治疗时机。本文通过分析病例临床资料，系统总结该病的临床特点，回顾耳显微镜下乳突改良根治手术的要点，综合国内外文献探讨该疾病的发病机制，旨在提高临床医师对该病诊断、鉴别诊断的认知能力及个体化手术策略制订，强调影像学在术前评估中的价值与选择合适手术方式的重要意义。方法报道1例7岁男性患儿因右耳反复流脓2年就诊，曾多次诊断为急性中耳炎，抗感染治疗效果不佳。于广州中医药大学第一附属医院耳鼻喉科完善检查后明确诊断为先天性巨大中耳胆脂瘤合并中耳畸形。术前评估为Potsic Ⅳ期。经术前讨论及家属知情同意，患儿接受耳显微镜下乳突改良根治术，在保护原有解剖结构的情况下彻底清除病变组织。结果术后病理证实胆脂瘤诊断，随访患儿无耳鸣、眩晕、面瘫等术后并发症，可正常交流，暂无2次手术计划。结论首要表现为耳道流脓而无面痛、面瘫、眩晕的先天性中耳胆脂瘤易误诊为中耳炎，颞骨高分辨率计算机断层扫描、中耳磁共振成像与弥散加权成像等影像学对该病的早期定位、范围评估和治疗方案选择具有指导意义。在明确先天性胆脂瘤诊断后应尽快采取合适的手术方式彻底清除病变，尽可能保留原有结构，减少病变对周围组织及相关功能的不可逆损害，最大程度提高患者预后及远期生活质量。",
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  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "name": "唐语祺"
    },
    {
      "name": "何伟平"
    },
    {
      "name": "郭华民"
    },
    {
      "name": "刘景"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/cww7r6f45ra03.bib",
  "cited_by": 0,
  "doi": null,
  "fulltext_url": "http://www.chsr.cn/zh/article/doi/10.3969/j.issn.1672-4933.2026.05.010/",
  "id": "cww7r6f45ra03",
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  "language": "zh",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R"
    ]
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  "openalex": null,
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  "pmcid": null,
  "pmid": null,
  "published": "2026-09-01",
  "publisher": "Limited Liability Company of Chinese Scientific Journal of Hearing and Speech Rehabilitation",
  "ris": "https://research.draconitic.com/paper/cww7r6f45ra03.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:45:17Z",
      "native_id": "0d5b6b5301db421abaaa1392eb55bd9d",
      "source": "doaj",
      "url": "http://www.chsr.cn/zh/article/doi/10.3969/j.issn.1672-4933.2026.05.010/"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:R",
      "subfield": "general"
    }
  ],
  "title": "先天性巨大中耳胆脂瘤合并中耳畸形个案研究",
  "title_text": "先天性巨大中耳胆脂瘤合并中耳畸形个案研究",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:17Z",
  "url": "https://research.draconitic.com/paper/cww7r6f45ra03",
  "venue": "Zhongguo tingli yuyan kangfu kexue zazhi",
  "versions": []
}