{
  "abstract": "Polycystic ovary syndrome (PCOS), also known as polyendocrine metabolic ovarian syndrome (PMOS), is the most common endocrinologic disorder to affect women. Despite this, the pathophysiology of the disease is not entirely known. This has hindered the diagnosis of the disease and appropriate treatment for millions of individuals. In this Review, we discuss the proposed pathophysiology of PCOS from a translational perspective. We review the existing diagnostic criteria of PCOS and current management strategies. Finally, we discuss the long-term health sequelae associated with PCOS, future directions, and areas of needed research in this often-overlooked disease.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California, USA"
  ],
  "article_type": "review",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Jessica L. Chan",
      "orcid": "0000-0002-9423-6027"
    },
    {
      "affs": [
        0
      ],
      "name": "Irene Masini",
      "orcid": "0000-0002-6155-9022"
    },
    {
      "affs": [
        0
      ],
      "name": "Margareta Danuta Pisarska",
      "orcid": "0000-0003-1096-6506"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/d0qbkbwsy4xxy.bib",
  "cited_by": 17,
  "doi": "10.1172/jci202824",
  "fulltext_url": null,
  "id": "d0qbkbwsy4xxy",
  "issns": [
    "0021-9738",
    "1558-8238"
  ],
  "landing_url": "https://doi.org/10.1172/jci202824",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2743|Ovarian function and disorders"
    ]
  ],
  "openalex": "W7164739541",
  "pdf_url": null,
  "pmcid": "PMC13262721",
  "pmid": "42294900",
  "published": "2026-06-14",
  "publisher": "American Society for Clinical Investigation",
  "ris": "https://research.draconitic.com/paper/d0qbkbwsy4xxy.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:26:56Z",
      "native_id": "W7164739541",
      "source": "openalex",
      "url": "https://doi.org/10.1172/jci202824"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2743|Ovarian function and disorders",
      "subfield": "reproductive-child"
    }
  ],
  "title": "Polyendocrine metabolic ovarian syndrome (PMOS)/polycystic ovary syndrome (PCOS): current and future trends",
  "title_text": "Polyendocrine metabolic ovarian syndrome (PMOS)/polycystic ovary syndrome (PCOS): current and future trends",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T13:21:15Z",
  "url": "https://research.draconitic.com/paper/d0qbkbwsy4xxy",
  "venue": "Journal of Clinical Investigation",
  "versions": []
}