{
  "abstract": "This document describes the Statistical Analysis Plan (SAP) for PETRA, a randomised controlled trial in people with generalised anxiety disorder comparing pregabalin plus an antidepressant and standard care, with placebo plus an antidepressant and standard care, with respect to the primary outcome of the GAD-7 score at week 12.",
  "abstract_shown": true,
  "affiliations": [
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  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
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        0
      ],
      "name": "G. Lewis"
    },
    {
      "name": "N. Freemantle"
    },
    {
      "name": "H.-M. Dehbi"
    },
    {
      "name": "C. Clarke"
    },
    {
      "name": "E. Bordea"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/d0rxpxr56xcp6.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.09.01.26359217",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.09.01.26359217v1.full",
  "id": "d0rxpxr56xcp6",
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  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "psychiatry and clinical psychology"
    ],
    [
      "openalex",
      "3205|Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes"
    ]
  ],
  "openalex": "W7208716628",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.09.01.26359217v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/d0rxpxr56xcp6.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:47Z",
      "native_id": "10.64898/2026.09.01.26359217",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.09.01.26359217v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:psychiatry and clinical psychology",
      "subfield": "psychiatry"
    }
  ],
  "title": "PrEgabalin for Treatment Resistant generalised Anxiety disorder: statistical analysis plan for a randomised controlled trial",
  "title_text": "PrEgabalin for Treatment Resistant generalised Anxiety disorder: statistical analysis plan for a randomised controlled trial",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:47Z",
  "url": "https://research.draconitic.com/paper/d0rxpxr56xcp6",
  "venue": "medRxiv",
  "versions": []
}