{
  "abstract": "Purpose:: Vascular malformations of the head and neck pose therapeutic challenges due to complex anatomy and proximity to critical structures. Percutaneous sclerotherapy guided by digital subtraction angiography is effective for low-flow malformations but involves radiation and iodinated contrast. Contrast-enhanced ultrasound offers a radiation-free alternative with real-time visualisation of intralesional contrast.\n\nMethods:: We retrospectively analysed contrast-enhanced ultrasound-guided sclerotherapy procedures for head and neck malformations in children under 6 years performed since 2021, assessing feasibility, safety and clinical outcomes. Six interventions in six patients (44 days to 3.5 years) were included.\n\nResults:: Contrast-enhanced ultrasound confirmed intralesional needle placement in all cases without evidence of extralesional contrast leakage. Sclerotherapy with Fibrovein or Aethoxysklerol was successfully performed in every procedure. No contrast-related adverse events occurred and all patients showed at least temporary clinical improvement.\n\nConclusions:: Contrast-enhanced ultrasound therefore appears feasible and safe for guiding sclerotherapy of venolymphatic malformations in the head and neck, enabling real-time verification without ionising radiation or iodinated contrast. The technique may be particularly valuable in paediatric patients requiring repeated interventions.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Oral and Maxillofacial Surgery, Hannover Medical School, Germany",
    "Department of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Germany"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Fritjof Lentge",
      "orcid": "0000-0001-9871-8421"
    },
    {
      "affs": [
        0
      ],
      "name": "Philipp Jehn"
    },
    {
      "affs": [
        1
      ],
      "name": "Omar Abu-Fares"
    },
    {
      "affs": [
        0
      ],
      "name": "Max Lukas Linderkamp"
    },
    {
      "affs": [
        0
      ],
      "name": "Efthymios Papazacharias"
    },
    {
      "affs": [
        0
      ],
      "name": "Nils-Claudius Gellrich"
    },
    {
      "affs": [
        0
      ],
      "name": "Philippe Korn"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/d13wbwx6asgmm.bib",
  "cited_by": 0,
  "doi": "10.1177/1742271x261495660",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13696583/",
  "id": "d13wbwx6asgmm",
  "issns": [
    "1742-271X",
    "1743-1344"
  ],
  "landing_url": "https://doi.org/10.1177/1742271x261495660",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Research"
    ],
    [
      "openalex",
      "2746|Vascular Malformations and Hemangiomas"
    ]
  ],
  "openalex": "W7223565490",
  "pdf_url": "https://europepmc.org/articles/PMC13696583?pdf=render",
  "pmcid": "PMC13696583",
  "pmid": "42936113",
  "published": "2026-10-25",
  "publisher": "SAGE Publications",
  "ris": "https://research.draconitic.com/paper/d13wbwx6asgmm.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:55Z",
      "native_id": "PMC13696583",
      "source": "pmc",
      "url": "https://doi.org/10.1177/1742271x261495660"
    },
    {
      "first_seen": "2026-10-30T12:22:12Z",
      "native_id": "MED:42936113",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42936113"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Vascular Malformations and Hemangiomas",
      "subfield": "surgery"
    }
  ],
  "title": "Contrast‑enhanced ultrasound-guided sclerotherapy of vascular malformations in the head and neck: Initial clinical experience in a paediatric case series",
  "title_text": "Contrast‑enhanced ultrasound-guided sclerotherapy of vascular malformations in the head and neck: Initial clinical experience in a paediatric case series",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:33:54Z",
  "url": "https://research.draconitic.com/paper/d13wbwx6asgmm",
  "venue": "Ultrasound: Journal of the British Medical Ultrasound Society",
  "versions": []
}