{
  "abstract": "Macroautophagy (hereafter referred to as autophagy) is a dynamic pathway of cellular degradation and recycling that is conserved from yeast to humans. The products of autophagic degradation may be used for anabolic reactions during nutrient-limited conditions. Thus, autophagy serves both metabolic and quality control functions. However, the role of nucleolar proteins in autophagy remains largely unexplored. Here we identify Ribosomal RNA processing 8 (Rrp8) as a positive regulator of autophagy flux in the yeast Saccharomyces cerevisiae. Our work provides insight into the role of the conserved nucleolar protein Rrp8 in regulating cellular responses to starvation.",
  "abstract_shown": true,
  "affiliations": [
    "Biological Sciences, Oakland University, Rochester, MI, United States"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Swaroopa Badenahalli Narasimhaiah"
    },
    {
      "affs": [
        0
      ],
      "name": "Elizabeth Delorme-Axford"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/d9apay4rcxtt7.bib",
  "cited_by": 0,
  "doi": "10.17912/micropub.biology.002252",
  "fulltext_url": "https://www.micropublication.org/journals/biology/micropub-biology-002252",
  "id": "d9apay4rcxtt7",
  "issns": [
    "2578-9430"
  ],
  "landing_url": "https://doi.org/10.17912/micropub.biology.002252",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "QH301-705.5"
    ],
    [
      "openalex",
      "2713|Autophagy in Disease and Therapy"
    ]
  ],
  "openalex": "W7172308822",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-01",
  "publisher": "Caltech Library",
  "ris": "https://research.draconitic.com/paper/d9apay4rcxtt7.ris",
  "sources": [
    {
      "first_seen": "2026-11-06T14:21:02Z",
      "native_id": "105730ba6f9e4d1b8c5f702f1b48872d",
      "source": "doaj",
      "url": "https://doi.org/10.17912/micropub.biology.002252"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Autophagy in Disease and Therapy",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "The methyltransferase Rrp8 is a positive regulator of autophagy flux in Saccharomyces cerevisiae",
  "title_text": "The methyltransferase Rrp8 is a positive regulator of autophagy flux in Saccharomyces cerevisiae",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T14:20:16Z",
  "url": "https://research.draconitic.com/paper/d9apay4rcxtt7",
  "venue": "microPublication Biology",
  "versions": []
}