{
  "abstract": "Magnetic resonance spectroscopic imaging (MRSI) enables non-invasive mapping of neu-rometabolites levels across the human brain. Although spectral fitting and metabolite quan-tification are increasingly supported by mature software tools, the downstream processing of quantified metabolite maps remains heterogeneous across laboratories. Here, we introduce MRSIPrep, an open-source, modular, and reproducible post-quantification framework for whole-brain MRSI. MRSIPrep standardizes quality control, tissue correction, spatial nor- malization, atlas projection, and derivative generation from quantified metabolite maps and associated quality metrics. The framework produces voxelwise, regional, and connectomics-ready outputs together with automated quality-control reports. We describe the architecture of MRSIPrep and demonstrate its utility for reproducible MRSI analysis across datasets,acquisition protocols, and downstream applications.",
  "abstract_shown": true,
  "affiliations": [
    "Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; Division of Child"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "F. Lucchetti"
    },
    {
      "name": "E. Celereau"
    },
    {
      "name": "R. Jenni"
    },
    {
      "name": "J.-B. Ledoux"
    },
    {
      "name": "S. Eliez"
    },
    {
      "name": "F. Delavari"
    },
    {
      "name": "P. Hagmann"
    },
    {
      "name": "Y. Aleman-Gomez"
    },
    {
      "affs": [
        0
      ],
      "name": "A. Klauser"
    },
    {
      "affs": [
        0
      ],
      "name": "P. Klauser"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dajs58hwrq6yq.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.09.11.750896",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.09.11.750896v1.full",
  "id": "dajs58hwrq6yq",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.09.11.750896v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "neuroscience"
    ],
    [
      "openalex",
      "2741|Advanced MRI Techniques and Applications"
    ]
  ],
  "openalex": "W7213459326",
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.09.11.750896v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-11",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/dajs58hwrq6yq.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:22:44Z",
      "native_id": "10.64898/2026.09.11.750896",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.09.11.750896v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:neuroscience",
      "subfield": "neuroscience"
    }
  ],
  "title": "MRSIPrep: A Standardized Post-Quantification Framework for Preprocessing Whole-Brain Magnetic Resonance Spectroscopic Imaging",
  "title_text": "MRSIPrep: A Standardized Post-Quantification Framework for Preprocessing Whole-Brain Magnetic Resonance Spectroscopic Imaging",
  "type": "preprint",
  "updated_at": "2026-10-30T12:22:44Z",
  "url": "https://research.draconitic.com/paper/dajs58hwrq6yq",
  "venue": "bioRxiv",
  "versions": []
}