{
  "abstract": "Introduction and importance:: Spontaneous splenic rupture is a rare, potentially life-threatening complication of Plasmodium infection. It occurs more commonly in Plasmodium vivax malaria and rarely in Plasmodium falciparum infection.\n\nCase presentation:: We report the case of a 37-year-old male who presented with a history of alternate-day fever associated with headache and was found to have pancytopenia on laboratory evaluation. He was diagnosed with Plasmodium falciparum malaria. Despite antimalarial therapy, the patient had splenomegaly with splenic rupture leading to hemoperitoneum on imaging. Due to hemodynamic stability, he was managed conservatively with scrupulous monitoring, platelet transfusion, and antimalarial therapy.\n\nClinical discussion:: Malaria remains a major infectious disease in tropical and subtropical regions, with Plasmodium falciparum causing a substantial burden of severe disease. Travelers remain at risk despite effective chemoprophylaxis, particularly with incomplete adherence or early discontinuation.\n\nConclusion:: Splenic rupture is an uncommon but potentially life-threatening complication of malaria and may occur even after initiation of antimalarial therapy. Consequently, timely diagnosis and appropriate management are crucial to improve patient outcomes.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Internal Medicine, Nepalese Army Institute of Health Sciences, Kathmandu, Nepal",
    "Department of Internal Medicine, Shree Birendra Hospital, Kathmandu, Nepal"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Saurab Karki"
    },
    {
      "affs": [
        0
      ],
      "name": "Binita Thapa Chhetri",
      "orcid": "0009-0000-7275-2509"
    },
    {
      "affs": [
        0
      ],
      "name": "Anil Pathak"
    },
    {
      "affs": [
        0
      ],
      "name": "Rahul Gautam"
    },
    {
      "affs": [
        0
      ],
      "name": "Parool Khadka"
    },
    {
      "affs": [
        1
      ],
      "name": "Nirmal Shrestha"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/db1p0sqjjj125.bib",
  "cited_by": 0,
  "doi": "10.1097/rc9.0000000000001075",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13747510/",
  "id": "db1p0sqjjj125",
  "issns": [
    "2210-2612"
  ],
  "landing_url": "https://doi.org/10.1097/rc9.0000000000001075",
  "language": "en",
  "licence": "CC-BY-NC-SA-4.0",
  "licence_label": "CC BY-NC-SA 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2739|Malaria Research and Control"
    ]
  ],
  "openalex": "W7225692156",
  "pdf_url": "https://europepmc.org/articles/PMC13747510?pdf=render",
  "pmcid": "PMC13747510",
  "pmid": "43006067",
  "published": "2026-09-29",
  "publisher": "Wolters Kluwer Health",
  "ris": "https://research.draconitic.com/paper/db1p0sqjjj125.ris",
  "sources": [
    {
      "first_seen": "2026-11-12T12:23:33Z",
      "native_id": "PMC13747510",
      "source": "pmc",
      "url": "https://doi.org/10.1097/rc9.0000000000001075"
    },
    {
      "first_seen": "2026-11-12T15:22:43Z",
      "native_id": "MED:43006067",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/43006067"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2739|Malaria Research and Control",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Spontaneous splenic rupture secondary to Plasmodium falciparum malaria: a case report",
  "title_text": "Spontaneous splenic rupture secondary to Plasmodium falciparum malaria: a case report",
  "type": "peer-reviewed",
  "updated_at": "2026-11-13T12:24:32Z",
  "url": "https://research.draconitic.com/paper/db1p0sqjjj125",
  "venue": "International Journal of Surgery Case Reports",
  "versions": []
}