{
  "abstract": "BackgroundElevated blood pressure (BP) is common during hospitalization. Despite recommendations to avoid routine changes in antihypertensive therapy, clinical practice remains variable. Prospective data on whether elevated in-hospital BP identifies patients with hypertension after discharge are limited.\n\nMethodsAdults hospitalized for non-cardiac conditions with asymptomatic routine in-hospital BP [≥]140 and/or [≥]90 mmHg on at least two occasions separated by [≥]24 hours were prospectively enrolled. Antihypertensive therapy was managed at the discretion of treating physicians. Routine in-hospital BP, standardized research BP, and changes in antihypertensive therapy were recorded. Four weeks after discharge, participants underwent 24-hour ambulatory BP monitoring (ABPM).\n\nResultsAmong 50 participants, 42 (84%; 95% CI, 70.9 - 92.8) had hypertension on follow-up ABPM. Among 21 participants without known hypertension, 18 (86%) had previously unrecognized hypertension on follow-up ABPM; among 29 participants with known hypertension, 24 (83%) had uncontrolled hypertension. Antihypertensive therapy was changed during hospitalization in 26 participants (52%), with de-escalation more frequent than intensification. Hypertension on follow-up ABPM was present in 88.5% of participants with and 79.2% without in-hospital therapy changes. Standardized research BP, but not routine in-hospital BP, correlated with follow-up ABPM.\n\nConclusionAsymptomatic elevated routine in-hospital BP identified a population with a high prevalence of hypertension four weeks after discharge, including patients with and without previously diagnosed hypertension. These findings support structured post-discharge BP reassessment rather than assuming that elevated in-hospital BP is transient.\n\nURL: www.ClinicalTrials.gov; Unique identifier: NCT06132451\n\nO_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=199 SRC=\"FIGDIR/small/26365097v1_ufig1.gif\" ALT=\"Figure 1\"> View larger version (76K): org.highwire.dtl.DTLVardef@fc519borg.highwire.dtl.DTLVardef@151c2b4org.highwire.dtl.DTLVardef@c5b819org.highwire.dtl.DTLVardef@b98117_HPS_FORMAT_FIGEXP M_FIG C_FIG",
  "abstract_shown": true,
  "affiliations": [
    "University Hospital Basel and University of Basel"
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "name": "K. Hausknecht"
    },
    {
      "name": "M. Mayr"
    },
    {
      "name": "T. Breidthardt"
    },
    {
      "name": "T. Burkard"
    },
    {
      "affs": [
        0
      ],
      "name": "A. S. Vischer"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dczhsjxcpnjsj.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.10.08.26365097",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.10.08.26365097v1.full",
  "id": "dczhsjxcpnjsj",
  "issns": [],
  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.10.08.26365097v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "cardiovascular medicine"
    ],
    [
      "openalex",
      "2705|Blood Pressure and Hypertension Studies"
    ]
  ],
  "openalex": "W7221433678",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.10.08.26365097v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-08",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/dczhsjxcpnjsj.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:40Z",
      "native_id": "10.64898/2026.10.08.26365097",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.10.08.26365097v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:cardiovascular medicine",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Persistent Hypertension After Asymptomatic Elevated In-Hospital Blood Pressure: The INDEBP Study",
  "title_text": "Persistent Hypertension After Asymptomatic Elevated In-Hospital Blood Pressure: The INDEBP Study",
  "type": "preprint",
  "updated_at": "2026-10-30T12:20:40Z",
  "url": "https://research.draconitic.com/paper/dczhsjxcpnjsj",
  "venue": "medRxiv",
  "versions": []
}