{
  "abstract": "The accumulation of protein-bound uremic toxins and middle- to large-molecular-weight toxins in patients receiving maintenance hemodialysis (MHD) results in long-term complications. Hemadsorption (HA) can efficiently remove these uremic toxins and reduce the risk of long-term complications in MHD patients. The Chinese HA-MHD Consensus Working Group has revised and updated the 2021 Shanghai Expert Consensus on the Clinical Application of Haemoadsorption in Maintenance Haemodialysis Patients to further standardize clinical application of HA and reflect the latest evidence. Based on an extensive literature search, the Grading of Recommendations Assessment, Development and Evaluation framework, and the modified Delphi method, the working group formulated 27 evidence-based recommendations regarding patient populations, session frequency, treatment modalities, precautions, and adverse reactions. This consensus systematically delineates the clinical thresholds and rationales for utilizing HA across three core dimensions: routine treatment regimens, intensive treatment regimens, and long-term complication risk management to provide comprehensive guidance. Furthermore, the consensus provides detailed guidance on individualized operational parameters to maximize both safety and treatment efficacy. This consensus aims to provide the latest guiding opinions for the rational and standardized application of HA therapy in patients receiving MHD.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Nephrology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China",
    "Department of Nephrology, Rheumatology and Immunology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China",
    "Department of Nephrology, First Affiliated Hospital of Naval Medical University, Shanghai, China",
    "Department of Nephrology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China",
    "Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China",
    "Department of Nephrology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China",
    "Department of Nephrology, Sichuan Provincial People's Hospital, Chengdu, China",
    "Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China",
    "Department of Nephrology, Affiliated Hospital of Qinghai University, Xining, China",
    "Department of Nephrology, Xijing Hospital, Air Force Medical University, Xi'an, China",
    "Department of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China",
    "Department of Nephrology, Hainan General Hospital, Haikou, China",
    "Department of Nephrology, Minhang Hospital, Fudan University, Shanghai, China",
    "Department of Nephrology, Qilu Hospital, Shandong University, Jinan, China",
    "Department of Nephrology, First Affiliated Hospital of Guangxi Medical University, Nanning, China",
    "Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China",
    "Department of Nephrology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China",
    "Department of Nephrology, General Hospital of Ningxia Medical University, Yinchuan, China",
    "Department of Nephrology, Shanxi Provincial People's Hospital, Taiyuan, China",
    "Department of Nephrology, First Affiliated Hospital of Kunming Medical University, Kunming, China"
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 23,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Xiaohua Sheng"
    },
    {
      "affs": [
        1
      ],
      "name": "Wei Lu"
    },
    {
      "affs": [
        2
      ],
      "name": "Zhiyong Guo"
    },
    {
      "affs": [
        3
      ],
      "name": "Shan Mou"
    },
    {
      "affs": [
        3
      ],
      "name": "Zhaohui Ni"
    },
    {
      "affs": [
        4
      ],
      "name": "Xiaoqiang Ding"
    },
    {
      "affs": [
        5
      ],
      "name": "Yueyi Deng"
    },
    {
      "affs": [
        6
      ],
      "name": "Guisen Li"
    },
    {
      "affs": [
        7
      ],
      "name": "Jun Liu"
    },
    {
      "affs": [
        8
      ],
      "name": "Pengli Luo"
    },
    {
      "affs": [
        9
      ],
      "name": "Shiren Sun"
    },
    {
      "affs": [
        10
      ],
      "name": "Huiming Wang"
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    {
      "affs": [
        11
      ],
      "name": "Jiali Wei"
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    {
      "affs": [
        12
      ],
      "name": "Xudong Xu"
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    {
      "affs": [
        13
      ],
      "name": "Xiangdong Yang"
    },
    {
      "affs": [
        14
      ],
      "name": "Zhenhua Yang"
    },
    {
      "affs": [
        15
      ],
      "name": "Wen Zhang"
    },
    {
      "affs": [
        16
      ],
      "name": "Jianrong Zhao"
    },
    {
      "affs": [
        17
      ],
      "name": "Xiaoling Zhou"
    },
    {
      "affs": [
        18
      ],
      "name": "Xiaoshuang Zhou"
    },
    {
      "affs": [
        19
      ],
      "name": "Zhu Zhou"
    },
    {
      "affs": [
        1
      ],
      "name": "Gengru Jiang"
    },
    {
      "affs": [
        0
      ],
      "name": "Niansong Wang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ddgn92kwkamjc.bib",
  "cited_by": 0,
  "doi": "10.1016/j.xkme.2026.101528",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722071/?tool=EBI",
  "id": "ddgn92kwkamjc",
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  "landing_url": "https://europepmc.org/article/PMC/PMC13722071",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Review"
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      "2727|Dialysis and Renal Disease Management"
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  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722071/pdf/?tool=EBI",
  "pmcid": "PMC13722071",
  "pmid": "42965173",
  "published": "2026-09-11",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/ddgn92kwkamjc.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:21:37Z",
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2727|Dialysis and Renal Disease Management",
      "subfield": "general"
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  ],
  "title": "Clinical Application of Hemadsorption in Maintenance Hemodialysis Patients: An Adapted English Republication of the Chinese HA-MHD Consensus",
  "title_text": "Clinical Application of Hemadsorption in Maintenance Hemodialysis Patients: An Adapted English Republication of the Chinese HA-MHD Consensus",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:22:39Z",
  "url": "https://research.draconitic.com/paper/ddgn92kwkamjc",
  "venue": "Kidney medicine",
  "versions": []
}