{
  "abstract": "Guillain–Barré syndrome (GBS) is an acute immune-mediated polyradiculoneuropathy characterized by progressive weakness, areflexia, and variable autonomic dysfunction. Intracranial hemorrhage (ICH) is an extremely uncommon neurological complication associated with GBS and has been rarely described in the literature. We report a case of a 53-year-old female who presented with rapidly progressive quadriparesis and respiratory failure. Clinical findings and nerve conduction studies were suggestive of pure motor axonal GBS. The patient was treated with intravenous immunoglobulin (IVIG) at a dose of 0.4 g/kg/day for five days. During treatment, she developed sudden deterioration in sensorium, and computed tomography of the brain revealed pontine hemorrhage with perilesional edema. Platelet count and coagulation parameters remained within normal limits. Despite intensive supportive management, the patient developed cardiac arrest and could not be revived. Intracranial hemorrhage is a rare but potentially fatal complication in patients with GBS. Sudden neurological deterioration during the course of disease or IVIG therapy should prompt immediate neuroimaging evaluation.",
  "abstract_shown": true,
  "affiliations": [
    "Department of General Medicine, AIIMS, Bathinda, Punjab, India",
    "Department of Radiology, AIIMS, Bathinda, Punjab, India"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Preeti Singh Dhoat"
    },
    {
      "affs": [
        0
      ],
      "name": "Amandeep Kaur"
    },
    {
      "affs": [
        0
      ],
      "name": "Rohit Raina"
    },
    {
      "affs": [
        1
      ],
      "name": "Navdeep Kaur"
    },
    {
      "affs": [
        0
      ],
      "name": "Sonali Mina"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/der2bbprgr4h1.bib",
  "cited_by": 0,
  "doi": "10.4103/jfmpc.jfmpc_441_25",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722235/?tool=EBI",
  "id": "der2bbprgr4h1",
  "issns": [
    "2249-4863",
    "2278-7135"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13722235",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2728|Peripheral Neuropathies and Disorders"
    ]
  ],
  "openalex": "W7220857094",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722235/pdf/?tool=EBI",
  "pmcid": "PMC13722235",
  "pmid": "42964828",
  "published": "2026-07-01",
  "publisher": "Wolters Kluwer -- Medknow Publications",
  "ris": "https://research.draconitic.com/paper/der2bbprgr4h1.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:21:45Z",
      "native_id": "PMC:PMC13722235",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13722235"
    },
    {
      "first_seen": "2026-11-03T12:22:47Z",
      "native_id": "PMC13722235",
      "source": "pmc",
      "url": "https://doi.org/10.4103/jfmpc.jfmpc_441_25"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2728|Peripheral Neuropathies and Disorders",
      "subfield": "neurology"
    }
  ],
  "title": "Intracranial hemorrhage in a patient with Guillain–Barré syndrome following intravenous immunoglobulin therapy: A rare complication",
  "title_text": "Intracranial hemorrhage in a patient with Guillain–Barré syndrome following intravenous immunoglobulin therapy: A rare complication",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:22:47Z",
  "url": "https://research.draconitic.com/paper/der2bbprgr4h1",
  "venue": "Journal of family medicine and primary care",
  "versions": []
}