{
  "abstract": "Asthma exacerbation can be triggered by various forms of air pollution, including PM2.5 from wildfire smoke. This study aims to investigate the association between wildfire smoke PM2.5 exposure and asthma exacerbations in adults during the warm months (April-August) between 2006 and 2019. Using a case-crossover design, we analyzed 18,935 asthma exacerbation events and four matched control periods per event from the National Institutes of Health (NIH) All of Us research program. We used the conditional logistic regression to estimate the association (odds ratios [ORs]) between wildfire smoke PM2.5 exposure and asthma exacerbation, considering lag periods of 0-7 days and adjusting for temperature, precipitation, and humidity. Significant positive associations were observed across all lag periods, with adjusted ORs ranging from 1.27 (95% CI: 1.22-1.33) to 1.38 (95% CI: 1.32-1.44). Stratified analyses showed higher odds of asthma exacerbation among older adults, non-Hispanic Whites, midwestern residents, and those exposed in May. These findings highlight the potential contribution of wildfire smoke PM2.5 to asthma exacerbations in adults and the importance of targeted public health strategies to reduce exposure during wildfire events.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Veterinary Physiology and Pharmacology Texas A&M University College Station TX USA.",
    "Department of Biobehavioral Health The Pennsylvania State University University Park PA USA.",
    "Department of Geography & Environmental Studies University of New Mexico Albuquerque NM USA.",
    "Department of Internal Medicine University of New Mexico Albuquerque NM USA.",
    "University of New Mexico Comprehensive Cancer Center Albuquerque NM USA.",
    "Lung Cancer Program Lovelace Biomedical Research Institute Albuquerque NM USA.",
    "Earth Data Analysis Center (EDAC) University of New Mexico Albuquerque NM USA.",
    "Center for Health Equity and Preparedness College of Nursing University of New Mexico Albuquerque NM USA.",
    "Department of Geography and Environmental Studies New Mexico State University Las Cruces NM USA.",
    "Department of Geography The Pennsylvania State University University Park PA USA.",
    "Social Science Research Institute (SSRI) The Pennsylvania State University University Park PA USA.",
    "Department of Pharmaceutical Sciences College of Pharmacy University of New Mexico Albuquerque NM USA.",
    "Institute for Computational and Data Sciences (ICDS) The Pennsylvania State University University Park PA USA."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Yanhong Huang"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Li Luo"
    },
    {
      "affs": [
        3,
        4,
        5
      ],
      "name": "Shuguang Leng"
    },
    {
      "affs": [
        2,
        6
      ],
      "name": "Su Zhang"
    },
    {
      "affs": [
        7
      ],
      "name": "Roberta P Lavin"
    },
    {
      "affs": [
        8
      ],
      "name": "Michaela Buenemann",
      "orcid": "0000-0002-5139-739X"
    },
    {
      "affs": [
        9,
        10
      ],
      "name": "Yan Lin"
    },
    {
      "affs": [
        11
      ],
      "name": "Matthew Campen"
    },
    {
      "affs": [
        1,
        12
      ],
      "name": "Xi Gong",
      "orcid": "0000-0001-7899-6213"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dhdfbdq3c9teh.bib",
  "cited_by": 0,
  "doi": "10.1029/2026gh001972",
  "fulltext_url": "https://europepmc.org/articles/PMC13744005",
  "id": "dhdfbdq3c9teh",
  "issns": [
    "2471-1403"
  ],
  "landing_url": "https://europepmc.org/article/MED/42999790",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2307|Air Quality and Health Impacts"
    ]
  ],
  "openalex": "W7225454473",
  "pdf_url": "https://europepmc.org/articles/PMC13744005?pdf=render",
  "pmcid": "PMC13744005",
  "pmid": "42999790",
  "published": "2026-11-07",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/dhdfbdq3c9teh.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T15:20:34Z",
      "native_id": "MED:42999790",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42999790"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2307|Air Quality and Health Impacts",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Asthma Exacerbations Following Wildfire Smoke PM2.5 Exposure Among U.S. Adults.",
  "title_text": "Asthma Exacerbations Following Wildfire Smoke PM2.5 Exposure Among U.S. Adults.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T15:20:34Z",
  "url": "https://research.draconitic.com/paper/dhdfbdq3c9teh",
  "venue": "GeoHealth",
  "versions": []
}