{
  "abstract": "This study evaluated the radiation tolerance, biomass production, vitamin biosynthesis, and whole-proteome response of three edible extremotolerant microorganisms, i.e., Debaryomyces hansenii DSM 3428, Bacillus subtilis DSM 10, and Limosilactobacillus reuteri DSM 20016, under a Martian mission-relevant ionizing radiation dose rate. Cultures were exposed to Martian cruise and Martian surface dose rates of gamma ionizing radiation, using γ-rays of a 60Co source. Biomass yield and riboflavin content of irradiated cultures were analyzed. Proteomic analyses were conducted for the bacteria B. subtilis and L. reuteri, for which well-annotated reference genomes and proteomes were available. Also, post-irradiation regrowth characteristics were tested. D. hansenii and B. subtilis showed no significant impairment in growth rate post-irradiation, biomass production, or riboflavin synthesis during chronic exposure, and normal post-irradiation regrowth, similar to non-exposed cultures. In contrast, L. reuteri exhibited a higher radiation sensitivity, with a reduced biomass yield in the irradiated cultures, and an altered post-irradiation growth profile.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "Article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "name": "Gabriele Ellena"
    },
    {
      "name": "Arianna Mazzoli",
      "orcid": "0000-0003-4096-443X"
    },
    {
      "name": "Surya Gupta"
    },
    {
      "name": "Irina Spacova"
    },
    {
      "name": "Natalie Leys"
    },
    {
      "name": "Sarah Lebeer"
    },
    {
      "name": "Felice Mastroleo",
      "orcid": "0000-0002-9815-8038"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dmsgv65tptsvd.bib",
  "cited_by": 0,
  "doi": "10.1016/j.isci.2026.117979",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13720614/?tool=EBI",
  "id": "dmsgv65tptsvd",
  "issns": [
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  ],
  "landing_url": "https://www.cell.com/iscience/fulltext/S2589-0042(26)03362-6",
  "language": "eng",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "http://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Article"
    ],
    [
      "heading",
      "Microbiology"
    ],
    [
      "heading",
      "Nutrition"
    ],
    [
      "heading",
      "Space sciences"
    ],
    [
      "openalex",
      "3103|Planetary Science and Exploration"
    ]
  ],
  "openalex": "W7223413958",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13720614/pdf/?tool=EBI",
  "pmcid": "PMC13720614",
  "pmid": "42964785",
  "published": "2026-10-23",
  "publisher": "Elsevier BV",
  "ris": "https://research.draconitic.com/paper/dmsgv65tptsvd.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:16Z",
      "native_id": "10.1016/j.isci.2026.117979",
      "source": "feed-cell",
      "url": "https://www.cell.com/iscience/fulltext/S2589-0042(26)03362-6"
    },
    {
      "first_seen": "2026-10-30T12:17:49Z",
      "native_id": "10.1016/j.isci.2026.117979",
      "source": "crossref",
      "url": "https://linkinghub.elsevier.com/retrieve/pii/S2589004226033626"
    },
    {
      "first_seen": "2026-10-31T12:21:37Z",
      "native_id": "PMC:PMC13720614",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13720614"
    },
    {
      "first_seen": "2026-11-03T12:21:27Z",
      "native_id": "PMC13720614",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.isci.2026.117979"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "heading:Microbiology",
      "subfield": "microbiology"
    },
    {
      "field": "medicine",
      "origin": "heading:Nutrition",
      "subfield": "nutrition"
    }
  ],
  "title": "Molecular profile of micronutrient-producing microorganisms following Martian mission-relevant ionizing radiation dose rate exposure",
  "title_text": "Molecular profile of micronutrient-producing microorganisms following Martian mission-relevant ionizing radiation dose rate exposure",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:21:27Z",
  "url": "https://research.draconitic.com/paper/dmsgv65tptsvd",
  "venue": "iScience",
  "versions": []
}