{
  "abstract": "Aspergillus endocarditis is a rare, life-threatening infection in which blood cultures are almost invariably negative. We report an exceptional case of blood culture-positive native aortic valve endocarditis caused by Aspergillus niger, presenting with acute limb ischemia. Concordant isolation of A. niger from peripheral blood cultures, embolic material, and resected valve tissue provided robust microbiological confirmation. Early surgical valve replacement combined with susceptibility-guided antifungal therapy enabled prompt targeted management and a favorable clinical outcome.",
  "abstract_shown": true,
  "affiliations": [
    "Medical Faculty, Johannes Kepler University, Linz, Austria.",
    "Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine 4 - Pneumology, Kepler University Hospital, Krankenhausstrasse 9, Linz, 4021, Austria.",
    "Department of Cardio-Thoracic and Vascular Surgery, Johannes Kepler University Hospital Linz, Austria.",
    "Ignaz Semmelweis Institut, Interuniversity Institute for Infection Research, Vienna, Austria."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Silvia Taurian"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Matthias Neuböck"
    },
    {
      "affs": [
        2
      ],
      "name": "Mohsen Alavian"
    },
    {
      "affs": [
        0,
        1,
        3
      ],
      "name": "Helmut Salzer"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dp47fq38ps8ec.bib",
  "cited_by": 0,
  "doi": "10.1016/j.mmcr.2026.100828",
  "fulltext_url": "https://europepmc.org/articles/PMC13679304",
  "id": "dp47fq38ps8ec",
  "issns": [
    "2211-7539"
  ],
  "landing_url": "https://europepmc.org/article/MED/42899160",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2713|Infective Endocarditis Diagnosis and Management"
    ]
  ],
  "openalex": "W7221156858",
  "pdf_url": "https://europepmc.org/articles/PMC13679304?pdf=render",
  "pmcid": "PMC13679304",
  "pmid": "42899160",
  "published": "2026-10-09",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/dp47fq38ps8ec.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:37Z",
      "native_id": "MED:42899160",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42899160"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Infective Endocarditis Diagnosis and Management",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Blood culture-positive Aspergillus niger native aortic valve endocarditis presenting as acute lower limb ischemia: a case report.",
  "title_text": "Blood culture-positive Aspergillus niger native aortic valve endocarditis presenting as acute lower limb ischemia: a case report.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:37Z",
  "url": "https://research.draconitic.com/paper/dp47fq38ps8ec",
  "venue": "Medical mycology case reports",
  "versions": []
}