{
  "abstract": "To overcome the application limitations of linalool, including its high volatility and poor stability, mesoporous silica MCM-41 was used as the carrier, and N-isopropylacrylamide (NIPAM) was employed as the thermosensitive monomer in this study. Acrylamide (AM) was introduced to modulate the lower critical solution temperature (LCST) of poly(N-isopropylacrylamide) (PNIPAM), while N,N′-methylenebis(acrylamide) (BIS), used as a cross-linking agent, was added to enhance structural stability, thus constructing the MCM-41-PNIPAM thermosensitive composite sustained-release system. Characterization results confirmed the successful synthesis of the target material, whose LCST increased to 82–85 °C with the increasing AM doping ratio. Sustained-release experiments indicated that the release rate of linalool significantly increased when the environmental temperature exceeded the LCST. Antibacterial tests revealed that the composite exhibited a remarkable inhibitory effect on Bacillus subtilis, Staphylococcus aureus, and Escherichia coli following the temperature-triggered release of linalool. Moreover, the antibacterial effect could be precisely controlled by regulating the ambient temperature, thereby modulating the release. This study presents a new strategy for the stabilized application of linalool, achieves an intelligent response effect of “temperature-triggered and on-demand release,” and offered a universal method for constructing intelligent preservation systems.",
  "abstract_shown": true,
  "affiliations": [
    "Chinese Academy of Agricultural Sciences , , ,",
    "China Tobacco Shandong Industrial Co., Ltd. , ,",
    "Chinese Academy of Sciences , , , ,"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Zhenhui Gao"
    },
    {
      "affs": [
        1
      ],
      "name": "Yanhua Lu"
    },
    {
      "affs": [
        1
      ],
      "name": "Fengfeng Zhang"
    },
    {
      "affs": [
        1
      ],
      "name": "Wenlong Bao"
    },
    {
      "affs": [
        1
      ],
      "name": "Xinhua Song"
    },
    {
      "affs": [
        0
      ],
      "name": "Fanyu Kong"
    },
    {
      "affs": [
        2
      ],
      "name": "Rongning Liang",
      "orcid": "0000-0002-9693-1242"
    },
    {
      "affs": [
        0
      ],
      "name": "Dean Song",
      "orcid": "0000-0003-1951-0839"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dqcwrwmevzhm1.bib",
  "cited_by": 0,
  "doi": "10.1021/acsomega.6c04870",
  "fulltext_url": null,
  "id": "dqcwrwmevzhm1",
  "issns": [
    "2470-1343"
  ],
  "landing_url": "https://pubs.acs.org/acsodf/article/doi/10.1021/acsomega.6c04870/5459658/Smart-Thermosensitive-Mesoporous-Silica-Composites",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2505|Mesoporous Materials and Catalysis"
    ]
  ],
  "openalex": "W7224112755",
  "pdf_url": "https://pubs.acs.org/doi/pdf/10.1021/acsomega.6c04870",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-28",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/dqcwrwmevzhm1.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:40Z",
      "native_id": "10.1021/acsomega.6c04870",
      "source": "crossref",
      "url": "https://pubs.acs.org/acsodf/article/doi/10.1021/acsomega.6c04870/5459658/Smart-Thermosensitive-Mesoporous-Silica-Composites"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:2505|Mesoporous Materials and Catalysis",
      "subfield": "materials-polymers"
    }
  ],
  "title": "Smart Thermosensitive Mesoporous Silica Composites for Precisely Triggered Linalool Release",
  "title_text": "Smart Thermosensitive Mesoporous Silica Composites for Precisely Triggered Linalool Release",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:40Z",
  "url": "https://research.draconitic.com/paper/dqcwrwmevzhm1",
  "venue": "ACS Omega",
  "versions": []
}