{
  "abstract": "Basement membranes (BMs) are dense, sheet-like extracellular matrices that surround animal tissues and provide mechanical and signaling functions. Tissue BMs are compositionally unique, with the presence and abundance of numerous components tailored to meet tissue-specific needs. How BMs establish and maintain distinct compositions remains poorly understood. Here, we investigate how the BM protein agrin is uniquely concentrated in the C. elegans pharyngeal BM. Through tissue-specific expression and live imaging, our results suggest that a combination of pharyngeal-specific expression and high BM affinity for binding agrin ensures the unique enrichment of agrin in the pharyngeal BM.",
  "abstract_shown": true,
  "affiliations": [
    "Biology, Duke University, Durham, NC, United States."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "C Teresa Ibeanu"
    },
    {
      "affs": [
        0
      ],
      "name": "Sandhya Srinivasan"
    },
    {
      "affs": [
        0
      ],
      "name": "Qiuyi Chi"
    },
    {
      "affs": [
        0
      ],
      "name": "David R Sherwood"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dqesdjbrc517y.bib",
  "cited_by": 0,
  "doi": "10.17912/micropub.biology.002449",
  "fulltext_url": "https://europepmc.org/articles/PMC13741015",
  "id": "dqesdjbrc517y",
  "issns": [
    "2578-9430"
  ],
  "landing_url": "https://europepmc.org/article/MED/42997129",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1307|Cellular Mechanics and Interactions"
    ]
  ],
  "openalex": "W7223147291",
  "pdf_url": "https://europepmc.org/articles/PMC13741015?pdf=render",
  "pmcid": "PMC13741015",
  "pmid": "42997129",
  "published": "2026-10-21",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/dqesdjbrc517y.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T15:20:41Z",
      "native_id": "MED:42997129",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42997129"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1307|Cellular Mechanics and Interactions",
      "subfield": "cell-biology"
    }
  ],
  "title": "The C. elegans pharyngeal basement membrane has a high affinity for binding agrin.",
  "title_text": "The C. elegans pharyngeal basement membrane has a high affinity for binding agrin.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T15:20:41Z",
  "url": "https://research.draconitic.com/paper/dqesdjbrc517y",
  "venue": "MicroPublication biology",
  "versions": []
}