{
  "abstract": "This study evaluated the physiological impacts of acute-exposure of tambaqui (Colossoma macropomum) to different concentrations of cellulose acetate nanoparticles at different sampling times. A total of 120 juvenile C. macropomum (38.91 ± 5.57 g and 13.76 ± 0.74 cm in total length) were distributed in 12 tanks of 150 L, in a recirculating aquaculture system (RAS). The juveniles were kept in water containing cellulose acetate nanoparticles (CANs) at four different concentrations (treatments): 0 mg L⁻¹, 0.01 mg L⁻¹, 0.10 mg L⁻¹ and 1.00 mg L⁻¹. Blood samples were collected after 1 and 24 h of exposure. The juveniles were then relocated to a tank with clean water, where they remained for another 24 h, after which a new blood sample was collected (24 h). Hemoglobin, serum protein and globulin were reduced after 1 h of exposure for the group exposed to 1.00 mg L⁻¹ of CANs. Glucose levels increased after 24 h for the groups exposed to 0.10 and 1.00 mg L⁻¹. Urea increased after 1 h for the groups exposed to 0.10 and 1.00 mg L⁻¹. Triglycerides and cholesterol were reduced both after 1 h and 24 h of exposure for the 1.00 mg L⁻¹ group, returning to baseline levels at 24 h. The activities of aspartate aminotransferase (AST) and alanine aminotransferase were altered after 24 h. Albumin was lower after 1 h and 24 h compared to after 24 h for the 1.00 mg L⁻¹ group. Exposure of juvenile C. macropomum to CANs caused transient physiological changes, with partial recovery being observed after transfer to clean water.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Metallurgical and Materials Engineering, Federal University of Minas Gerais (UFMG), Av. Antônio Carlos, 6627 - Campus da UFMG, Pampulha, Belo Horizonte, MG, Brazil. camilaoliveira080@gmail.com.",
    "Department of Metallurgical and Materials Engineering, Federal University of Minas Gerais (UFMG), Av. Antônio Carlos, 6627 - Campus da UFMG, Pampulha, Belo Horizonte, MG, Brazil.",
    "Departamento de Zootecnia, Laboratório de Aquacultura, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, n° 6627, Belo Horizonte, CEP 30161- 970, MG, Brazil.",
    "Department of Engineering, Federal University of Lavras, PO Box 3037, Lavras, 372000-900, MG, Brazil."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Camila Gomes de Oliveira",
      "orcid": "0000-0003-1260-9529"
    },
    {
      "affs": [
        1
      ],
      "name": "Túlio Pacheco Boaventura",
      "orcid": "0000-0002-6143-5417"
    },
    {
      "affs": [
        2
      ],
      "name": "Fábio Aremil Costa Dos Santos",
      "orcid": "0000-0001-5682-8040"
    },
    {
      "affs": [
        2
      ],
      "name": "André de Sena Souza"
    },
    {
      "affs": [
        3
      ],
      "name": "Sidney Dos Santos Silva",
      "orcid": "0000-0003-2807-2957"
    },
    {
      "affs": [
        2
      ],
      "name": "Imaculada de Morais Carvalho Ananias"
    },
    {
      "affs": [
        3
      ],
      "name": "Camila Silva Brey Gil",
      "orcid": "0000-0002-0767-3123"
    },
    {
      "affs": [
        2
      ],
      "name": "Ronald Kennedy Luz",
      "orcid": "0000-0002-1021-5772"
    },
    {
      "affs": [
        1
      ],
      "name": "Rodrigo Lambert Oréfice",
      "orcid": "0000-0002-6046-4056"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dsvb5azrw5394.bib",
  "cited_by": 0,
  "doi": "10.1007/s10646-026-03174-w",
  "fulltext_url": "https://europepmc.org/articles/PMC13694297",
  "id": "dsvb5azrw5394",
  "issns": [
    "0963-9292",
    "1573-3017"
  ],
  "landing_url": "https://europepmc.org/article/MED/42909697",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2307|Environmental Toxicology and Ecotoxicology"
    ]
  ],
  "openalex": "W7223300642",
  "pdf_url": "https://europepmc.org/articles/PMC13694297?pdf=render",
  "pmcid": "PMC13694297",
  "pmid": "42909697",
  "published": "2026-10-23",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/dsvb5azrw5394.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:03Z",
      "native_id": "MED:42909697",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42909697"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2307|Environmental Toxicology and Ecotoxicology",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Cellulose acetate nanoparticles: impacts of concentration and exposure time on the biochemistry and hematology of juvenile Colossoma macropomum.",
  "title_text": "Cellulose acetate nanoparticles: impacts of concentration and exposure time on the biochemistry and hematology of juvenile Colossoma macropomum.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:03Z",
  "url": "https://research.draconitic.com/paper/dsvb5azrw5394",
  "venue": "Ecotoxicology (London, England)",
  "versions": []
}