{
  "abstract": "Background\n\nEmotional distress in pulmonary fibrosis remains under-recognised and poorly addressed. This study assessed changes in anxiety and depressive symptoms following an individualised psychological intervention.Methods\n\nSingle-centre, single-arm before-and-after observational study of an individualised psychological intervention delivered in routine ILD care, combining acceptance and commitment therapy, humanistic-existential techniques, and psychophysiological interventions. Anxiety and depressive symptoms were assessed with the Hospital Anxiety and Depression Scale (HADS) before and after the intervention. Patient- and caregiver-reported experience measures (PREMs) were collected. Response was analysed across characteristics defined before any analysis of outcome data (age, sex, disease severity [ILD-GAP], frailty [CFS], time since diagnosis, and baseline HADS).Results\n\nThirty patients were included (50.0% women; mean age 71.0 years). At baseline, 76.7% scored ≥8 on HADS-anxiety and 76.7% on HADS-depression, indicatingclinically relevant symptom risk. Six patients discontinued (lung transplantation, palliative care, or death; n = 2 each). Among 24 evaluable patients, mean HADS-anxiety decreased from 11.3 to 6.6 (mean difference 4.7; 97.5% CI 2.6-6.9; p < 0.001) and HADS-depression from 10.7 to 5.5 (mean difference 5.2; 97.5% CI 3.2-7.2; p < 0.001). HADS-anxiety score improved in 19 patients, was unchanged in 3 and worsened in 2; HADS-depression score improved in 20, was unchanged in 2 and worsened in 2. No patient worsened in HADS category. No differences in response were detected by age, sex, disease severity, frailtyor time since diagnosis. Patient- and caregiver-reported experience scores were high (totalscore 9.4 [SD 0.7] in patients and 9.5 [SD 0.7] in caregivers).Conclusion\n\nIn this uncontrolled study, an individualised psychological intervention was associated with reduced anxiety and depressive symptoms and a lower proportion of patients at risk of clinically relevant anxiety and depression in pulmonary fibrosis. These findings suggest the potential of psychological care within routine ILD follow-up and require confirmation in randomised controlled trials.",
  "abstract_shown": true,
  "affiliations": [
    "Psychology Department, Hospital General de Granollers, Granollers, Barcelona, Spain.",
    "Respiratory Department, Hospital General de Granollers, Granollers, Barcelona, Spain.",
    "Patient Experience Department, Hospital General de Granollers, Granollers, Barcelona, Spain.",
    "Research and Statistics Unit, Hospital General de Granollers, Granollers, Barcelona, Spain.",
    "Department of Medicine, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Barcelona, Spain."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Eda Sara Persentili"
    },
    {
      "affs": [
        1
      ],
      "name": "Mireia Baiges"
    },
    {
      "affs": [
        2
      ],
      "name": "Marta Jiménez"
    },
    {
      "affs": [
        3
      ],
      "name": "Miguel Sampayo-Cordero"
    },
    {
      "affs": [
        1
      ],
      "name": "Yolanda Galea-Colon"
    },
    {
      "affs": [
        0
      ],
      "name": "Raquel Cuevas"
    },
    {
      "affs": [
        1,
        4
      ],
      "name": "Jaume Bordas-Martinez",
      "orcid": "0000-0003-4027-8907"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dv07q8tqkvspe.bib",
  "cited_by": 0,
  "doi": "10.1080/07853890.2026.2743870",
  "fulltext_url": "https://europepmc.org/articles/PMC13700519",
  "id": "dv07q8tqkvspe",
  "issns": [
    "0785-3890",
    "1365-2060"
  ],
  "landing_url": "https://europepmc.org/article/MED/42908336",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2740|Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis"
    ]
  ],
  "openalex": "W7223169929",
  "pdf_url": "https://europepmc.org/articles/PMC13700519?pdf=render",
  "pmcid": "PMC13700519",
  "pmid": "42908336",
  "published": "2026-10-22",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/dv07q8tqkvspe.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:53Z",
      "native_id": "MED:42908336",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42908336"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2740|Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis",
      "subfield": "general"
    }
  ],
  "title": "The potential of psychological intervention to decrease the risk of anxiety and depression in pulmonary fibrosis.",
  "title_text": "The potential of psychological intervention to decrease the risk of anxiety and depression in pulmonary fibrosis.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:53Z",
  "url": "https://research.draconitic.com/paper/dv07q8tqkvspe",
  "venue": "Annals of medicine",
  "versions": []
}