{
  "abstract": "Rapid processing of Perfusion and Diffusion (RAPID) software for CT perfusion (CTP) is a valuable tool for the evaluation of acute ischemic stroke and therapeutic decision-making in extended therapeutic windows. However, automated maps should not be interpreted in isolation. A structured, pattern-based approach, integrating qualitative visual assessment with automated quantitative output and clinical information to refine therapeutic selection, remains essential to mitigate pitfalls and optimize patient care. The aim of this article is to provide an educational pictorial review based on selected illustrative cases of the most common imaging patterns, interpretive pitfalls, and technical features of CTP processed with RAPID software in acute ischemic stroke, that may serve as a practical guide for radiologists and neuroradiologists.\n\nKey Points: Question How can radiologists effectively interpret automated RAPID CT perfusion maps in acute ischemic stroke while avoiding common technical traps, diagnostic pitfalls, and anatomical limitations?\n\nFindings Integrating qualitative visual assessment, quantitative RAPID outputs, and clinical-vascular data within a structured workflow minimizes diagnostic errors and optimizes patient selection for reperfusion.\n\nCritical relevance statement This educational pictorial review provides a practical, pattern-based approach to RAPID CT perfusion interpretation, highlighting clinical applications, technical limitations, software variability, and diagnostic pitfalls to advance everyday neuroradiological practice and personalized stroke management.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "Andrea Buoso"
    },
    {
      "name": "Caterina Bernetti",
      "orcid": "0000-0002-7377-6067"
    },
    {
      "name": "Michele Tondo"
    },
    {
      "name": "Ilenia Barbalace"
    },
    {
      "name": "Teresa Giannarelli"
    },
    {
      "name": "Michele Pillitteri"
    },
    {
      "name": "Andrea Romano"
    },
    {
      "name": "Alessandro Bozzao"
    },
    {
      "name": "Bruno Beomonte Zobel"
    },
    {
      "name": "Carlo A. Mallio"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dvcr9gbpzye2c.bib",
  "cited_by": 0,
  "doi": "10.1186/s13244-026-02427-w",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661866/?tool=EBI",
  "id": "dvcr9gbpzye2c",
  "issns": [
    "1869-4101"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13661866",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2713|Acute Ischemic Stroke Management"
    ]
  ],
  "openalex": "W7221641688",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661866/pdf/?tool=EBI",
  "pmcid": "PMC13661866",
  "pmid": null,
  "published": "2026-10-13",
  "publisher": "Springer Science and Business Media LLC",
  "ris": "https://research.draconitic.com/paper/dvcr9gbpzye2c.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:29Z",
      "native_id": "PMC:PMC13661866",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13661866"
    },
    {
      "first_seen": "2026-10-30T12:20:33Z",
      "native_id": "10.1186/s13244-026-02427-w",
      "source": "crossref",
      "url": "https://link.springer.com/10.1186/s13244-026-02427-w"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Acute Ischemic Stroke Management",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "RAPID perfusion CT in acute ischemic stroke: an educational pictorial review of common patterns, pearls, and pitfalls",
  "title_text": "RAPID perfusion CT in acute ischemic stroke: an educational pictorial review of common patterns, pearls, and pitfalls",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:33Z",
  "url": "https://research.draconitic.com/paper/dvcr9gbpzye2c",
  "venue": "Insights into imaging",
  "versions": []
}