{
  "abstract": "Pest management often requires the rotation of insecticides, sequentially exposing non-target populations to different compounds. In a two-phased experiment, we assessed whether exposure to the pesticide chlorpyrifos induces rapid evolution in the non-target species Daphnia magna and quantified the response of control and pre-exposed populations to a second exposure to the same pesticide, another pesticide with the same mode of action (malathion), or a pesticide with another mode of action (deltamethrin). Chlorpyrifos selection induced rapid shifts in genotype composition and reduced genotype richness and strongly influenced population development following the second exposure. Chlorpyrifos-selected populations outperformed control populations when subsequently exposed to chlorpyrifos and malathion but underperformed when exposed to deltamethrin. Our results highlight an eco-evolutionary feedback in which rapid adaptive responses to a pesticide worsen the response when exposed to a different type of pesticide in non-target species, increasing vulnerability to common agricultural practices.",
  "abstract_shown": true,
  "affiliations": [
    "Laboratory of Freshwater Ecology, Evolution and Conservation, KU Leuven, Leuven, Belgium.",
    "Data Science Institute (DSI), Interuniversity Institute for Biostatistics and Statistical Bioinformatics (I-BioStat), Hasselt University, Hasselt, Belgium.",
    "Research Institute of Nature and Forest (INBO), Brussels, Belgium.",
    "Department of Fisheries Biology, Institute for Agricultural, Fisheries and Food Research (ILVO), Ostend, Belgium.",
    "Ecology, Evolution & Genetics (bDIV) Research Group, Department of Biology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.",
    "Leibniz Institute Für Gewasserökologie und Binnenfischerei (IGB), Berlin, Germany."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Rafaela A Almeida",
      "orcid": "0000-0002-5228-9091"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Maxime Fajgenblat",
      "orcid": "0000-0002-2233-1527"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Pieter Lemmens",
      "orcid": "0000-0002-3135-9724"
    },
    {
      "affs": [
        0
      ],
      "name": "Kiani Cuypers"
    },
    {
      "affs": [
        3
      ],
      "name": "Jade Maes",
      "orcid": "0009-0000-7253-9425"
    },
    {
      "affs": [
        4
      ],
      "name": "Kristien I Brans",
      "orcid": "0000-0002-0464-7720"
    },
    {
      "affs": [
        0,
        5
      ],
      "name": "Luc De Meester",
      "orcid": "0000-0001-5433-6843"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dy0at0zmag11n.bib",
  "cited_by": 0,
  "doi": "10.1111/ele.70459",
  "fulltext_url": "https://europepmc.org/articles/PMC13686550",
  "id": "dy0at0zmag11n",
  "issns": [
    "1461-023X",
    "1461-0248"
  ],
  "landing_url": "https://europepmc.org/article/MED/42905957",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1311|Evolution and Genetic Dynamics"
    ]
  ],
  "openalex": "W7223081671",
  "pdf_url": "https://europepmc.org/articles/PMC13686550?pdf=render",
  "pmcid": "PMC13686550",
  "pmid": "42905957",
  "published": "2026-10-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/dy0at0zmag11n.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:57Z",
      "native_id": "MED:42905957",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42905957"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1311|Evolution and Genetic Dynamics",
      "subfield": "genetics-genomics"
    }
  ],
  "title": "Eco-Evolutionary Feedback to a Pesticide Worsens the Impact of a Pesticide Switch in a Pivotal Freshwater Non-Target Species.",
  "title_text": "Eco-Evolutionary Feedback to a Pesticide Worsens the Impact of a Pesticide Switch in a Pivotal Freshwater Non-Target Species.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:57Z",
  "url": "https://research.draconitic.com/paper/dy0at0zmag11n",
  "venue": "Ecology letters",
  "versions": []
}