{
  "abstract": "Socioeconomic status (SES) is well recognized as an important determinant of cancer incidence and survival. However, its impact on outcomes in patients with mantle cell lymphoma (MCL) remains poorly characterized. We conducted a nationwide, population-based retrospective longitudinal study using German cancer registry data, including all patients diagnosed with MCL between 2013 and 2023. Regional SES was assessed annually at the district level using quintiles of the German Index of Socioeconomic Deprivation. The primary outcomes were 5-year absolute survival (AS) and relative survival (RS) as a proxy for disease-specific survival. A total of 8871 patients were included. Five-year AS and RS were 62.6% (95% CI, 61.5-63.7) and 72.1% (95% CI, 70.8-73.4), respectively. However, no meaningful differences in AS were observed between patients residing in districts of the lowest and highest SES quintiles (62.0% vs 63.1%). This nationwide population-based study indicates that regional socioeconomic deprivation was not associated with clinically relevant differences in survival outcomes among MCL patients in Germany between 2013 and 2023. These findings differ from previously described patterns in other lymphomas, suggesting that biological disease characteristics may exert a stronger influence on MCL survival than social determinants.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. s.vonkroge@uke.de.",
    "Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.",
    "Division of Social Determinants of Health, Department of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.",
    "Hamburg Cancer Registry, Ministry of Science, Research and Equality, Free and Hanseatic City of Hamburg, Hamburg, Germany."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Susanne von Kroge"
    },
    {
      "affs": [
        1
      ],
      "name": "Sabrina Klotz"
    },
    {
      "affs": [
        1
      ],
      "name": "Hanna Walk"
    },
    {
      "affs": [
        1
      ],
      "name": "Carsten Bokemeyer"
    },
    {
      "affs": [
        2
      ],
      "name": "Fabian Tetzlaff"
    },
    {
      "affs": [
        3
      ],
      "name": "Henrik Kusche",
      "orcid": "0000-0001-5400-6676"
    },
    {
      "name": "“LYSED” study group"
    },
    {
      "affs": [
        3
      ],
      "name": "Frederik Peters",
      "orcid": "0000-0001-5832-8410"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/dy3jazc85a0pj.bib",
  "cited_by": 0,
  "doi": "10.1038/s41408-026-01658-w",
  "fulltext_url": "https://europepmc.org/articles/PMC13722679",
  "id": "dy3jazc85a0pj",
  "issns": [
    "2044-5385"
  ],
  "landing_url": "https://europepmc.org/article/MED/42963359",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Article"
    ],
    [
      "openalex",
      "2734|Lymphoma Diagnosis and Treatment"
    ]
  ],
  "openalex": "W7224779982",
  "pdf_url": "https://europepmc.org/articles/PMC13722679?pdf=render",
  "pmcid": "PMC13722679",
  "pmid": "42963359",
  "published": "2026-10-30",
  "publisher": "Nature Publishing Group",
  "ris": "https://research.draconitic.com/paper/dy3jazc85a0pj.ris",
  "sources": [
    {
      "first_seen": "2026-11-02T03:21:21Z",
      "native_id": "MED:42963359",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42963359"
    },
    {
      "first_seen": "2026-11-04T12:21:27Z",
      "native_id": "PMC13722679",
      "source": "pmc",
      "url": "https://doi.org/10.1038/s41408-026-01658-w"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2734|Lymphoma Diagnosis and Treatment",
      "subfield": "general"
    }
  ],
  "title": "Socioeconomic deprivation does not affect survival outcomes in patients with mantle cell lymphoma: evidence from a German nationwide study.",
  "title_text": "Socioeconomic deprivation does not affect survival outcomes in patients with mantle cell lymphoma: evidence from a German nationwide study.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-04T12:21:27Z",
  "url": "https://research.draconitic.com/paper/dy3jazc85a0pj",
  "venue": "Blood cancer journal",
  "versions": []
}