{
  "abstract": "OBJECTIVE: To review the available evidence on post-treatment follow-up and recurrence management after cervical cancer. METHODS: We conducted a narrative review of the literature on surveillance modalities, and the management of pelvic and nodal recurrences. RESULTS: Most recurrences occur within three years of treatment, but the survival benefit of detection before symptom onset remains unproven. After fertility-sparing surgery, HPV testing is sensitive for detecting asymptomatic pelvic recurrence. After hysterectomy, most recurrences are symptomatic, and clinical examination has a higher diagnostic yield than HPV testing or vaginal vault cytology. After concurrent chemoradiotherapy (CRT), persistent HPV infection is associated with an increased recurrence risk, but its limited specificity and the absence of a validated HPV-based surveillance strategy restrict its clinical utility. MRI and FDG PET/CT are useful for response assessment and investigation of suspected recurrence, but evidence supporting routine imaging of asymptomatic patients is lacking. Intensive follow-up schedules have not improved recurrence detection or survival. Evidence on recurrence management is predominantly retrospective. Pelvic recurrences after primary surgery have been treated with CRT, supplemented by brachytherapy for vaginal involvement. In selected patients with central pelvic recurrence after CRT, complete surgical resection may provide prolonged survival, but carries substantial morbidity. Nodal recurrences outside previously irradiated fields have been treated with CRT. CONCLUSION: Available evidence supports a predominantly clinical, treatment-adapted follow-up. The survival benefit of intensive surveillance, routine imaging, or detecting asymptomatic recurrence remains uncertain. Recurrence management requires individualized multidisciplinary assessment based on disease extent, disease-free interval, and previous treatments.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 48,
  "authors": [
    {
      "name": "Aurélie Buffeteau"
    },
    {
      "name": "Abel Cordoba"
    },
    {
      "name": "Jean Levêque"
    },
    {
      "name": "Pascal Rousset"
    },
    {
      "name": "Isabelle Thomassin"
    },
    {
      "name": "Jean-Luc Brun"
    },
    {
      "name": "Xavier Carcopino"
    },
    {
      "name": "Lobna Ouldamer"
    },
    {
      "name": "Cyrille Huchon"
    },
    {
      "name": "Pauline Asseeva"
    },
    {
      "name": "Henri Azaïs"
    },
    {
      "name": "Sofiane Bendifallah"
    },
    {
      "name": "Jean-Luc Brun"
    },
    {
      "name": "Geoffroy Canlorbe"
    },
    {
      "name": "Cyrus Chargari"
    },
    {
      "name": "Pauline Chauvet"
    },
    {
      "name": "Abel Cordoba"
    },
    {
      "name": "Hélène Courcier"
    },
    {
      "name": "Yohann Dabi"
    },
    {
      "name": "Marion de Berti"
    },
    {
      "name": "Caroline Diguisto"
    },
    {
      "name": "Eva Fuss"
    },
    {
      "name": "Thomas Gaillard"
    },
    {
      "name": "Tristan Gauthier"
    },
    {
      "name": "Witold Gertych"
    },
    {
      "name": "Laurence Gladieff"
    },
    {
      "name": "Olivier Graesslin"
    },
    {
      "name": "Yohan Kerbage"
    },
    {
      "name": "Martin Koskas"
    },
    {
      "name": "Enora Laas"
    },
    {
      "name": "Aymeline Lacorre"
    },
    {
      "name": "Vincent Lavoué"
    },
    {
      "name": "Lise Lecointre"
    },
    {
      "name": "Fabrice Lecuru"
    },
    {
      "name": "François Margueritte"
    },
    {
      "name": "Alejandra Martinez"
    },
    {
      "name": "Paul-Jean Maternowski"
    },
    {
      "name": "Patrice Mathevet"
    },
    {
      "name": "Imane Menouer"
    },
    {
      "name": "Camille Mimoun"
    },
    {
      "name": "A Moureau"
    },
    {
      "name": "Antoine Netter"
    },
    {
      "name": "Charles-André Philip"
    },
    {
      "name": "Pascal Rousset"
    },
    {
      "name": "Claire Sanson"
    },
    {
      "name": "Isabelle Thomassin-Naggara"
    },
    {
      "name": "Cyril Touboul"
    },
    {
      "name": "Jean Levêque"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/e077zrynvk0g8.bib",
  "cited_by": 0,
  "doi": "10.1016/j.jogoh.2026.103315",
  "fulltext_url": null,
  "id": "e077zrynvk0g8",
  "issns": [
    "2468-8495",
    "2468-7847"
  ],
  "landing_url": "https://hal.science/hal-05850520v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "hal",
      "1.sdv.can"
    ],
    [
      "openalex",
      "2729|Endometrial and Cervical Cancer Treatments"
    ]
  ],
  "openalex": "W7224458702",
  "pdf_url": "https://www.sciencedirect.com/science/article/pii/S246878472600214X/pdf",
  "pmcid": null,
  "pmid": "42956933",
  "published": "2026-11-03",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/e077zrynvk0g8.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:20:53Z",
      "native_id": "hal-05850520",
      "source": "hal",
      "url": "https://hal.science/hal-05850520v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    },
    {
      "field": "medicine",
      "origin": "hal:1.sdv.can",
      "subfield": "oncology"
    }
  ],
  "title": "POST-TREATMENT SURVEILLANCE AND MANAGEMENT OF RECURRENT CERVICAL CANCER - A REVIEW FROM THE FRENCH CERVICAL CANCER GUIDELINES GROUP",
  "title_text": "POST-TREATMENT SURVEILLANCE AND MANAGEMENT OF RECURRENT CERVICAL CANCER - A REVIEW FROM THE FRENCH CERVICAL CANCER GUIDELINES GROUP",
  "type": "peer-reviewed",
  "updated_at": "2026-11-05T12:20:12Z",
  "url": "https://research.draconitic.com/paper/e077zrynvk0g8",
  "venue": "Journal of Gynecology Obstetrics and Human Reproduction",
  "versions": []
}