{
  "abstract": "Introduction: Cutaneous metastases can originate from different organ systems and reach the skin through various pathways. Hence, they can present in a wide range of clinical patterns.\n\nObjectives: We aimed to evaluate the clinical features of cutaneous metastases in a large, well-documented series and compare them with the literature.\n\nMethods: Patients diagnosed with cutaneous metastasis in a 20-year period were evaluated in this retrospective single-center study. Metastases of hematologic malignancies, melanoma, and major epithelial malignancies of skin were excluded.\n\nResults: In all, 105 patients were included in the study. The most common primary origin was breast (n=42), followed by oral and nasal mucosal squamous cell carcinoma (SCC) (n=7), and gastric cancer (n=6). Chest was the most commonly involved site (n=51), followed by head (n=26). Breast cancer and mucosal SCC tended to metastasize locally, while colon, bladder, lung, and gastric cancers had higher rates of distant metastasis. Fourteen patients (13.3%) presented with multiple clinical patterns. Patients most commonly presented with nodules (n=81), although sclerodermoid (n=12), carcinoma erysipeloides (n=11), and erythema annulare centrifugum-like (EAC-like) (n=9) presentations were observed at a higher rate than the literature. Among various nodular patterns, multiple isolated nodules were the most common. Ulceration was observed at the highest rate in the literature (31.4%), and was mostly associated with nodular metastases.\n\nConclusions: Cutaneous metastases can have a variety of presentations, sometimes with multiple patterns observed simultaneously. In the differential diagnosis of persistent EAC-like lesions, circumscribed sclerodermoid lesions, and ulcerated nodules not otherwise explained, cutaneous metastases should be considered.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Dermatology and Venereology, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Türkiye",
    "Department of Pathology, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Türkiye"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Armağan Kutlay",
      "orcid": "0000-0001-8380-6656"
    },
    {
      "affs": [
        1
      ],
      "name": "Şule Öztürk Sarı",
      "orcid": "0000-0003-0439-5954"
    },
    {
      "affs": [
        1
      ],
      "name": "Nesimi Büyükbabani",
      "orcid": "0000-0003-0472-4826"
    },
    {
      "affs": [
        0
      ],
      "name": "Can Baykal",
      "orcid": "0000-0001-6004-3166"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/e0aerms7nbnc1.bib",
  "cited_by": 0,
  "doi": "10.5826/dpc.1604a7227",
  "fulltext_url": "https://dpcj.org/index.php/dpc/article/view/7227",
  "id": "e0aerms7nbnc1",
  "issns": [
    "2160-9381"
  ],
  "landing_url": "https://doi.org/10.5826/dpc.1604a7227",
  "language": "en",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RL1-803"
    ],
    [
      "openalex",
      "2740|Metastasis and carcinoma case studies"
    ]
  ],
  "openalex": "W7224630401",
  "pdf_url": "https://dpcj.org/index.php/dpc/article/download/7227/3986",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-29",
  "publisher": "Mattioli1885",
  "ris": "https://research.draconitic.com/paper/e0aerms7nbnc1.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T14:22:34Z",
      "native_id": "017a285d1e244c40b65e791fc55bdfab",
      "source": "doaj",
      "url": "https://doi.org/10.5826/dpc.1604a7227"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2740|Metastasis and carcinoma case studies",
      "subfield": "general"
    }
  ],
  "title": "Cutaneous Metastases: An Update on Their Origins and Clinical Presentations",
  "title_text": "Cutaneous Metastases: An Update on Their Origins and Clinical Presentations",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T14:22:34Z",
  "url": "https://research.draconitic.com/paper/e0aerms7nbnc1",
  "venue": "Dermatology Practical & Conceptual",
  "versions": []
}