{
  "abstract": "Objectives: Juvenile nasopharyngeal angiofibroma is a highly vascular benign tumour affecting adolescent males. Our aim was to compare operative outcomes in embolised and non-embolised patients, with emphasis on tumour stage.\n\nMethods: A systematic review was conducted using three databases (PubMed, Scopus and Google Scholar) in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines.\n\nResults: Overall, 17 studies with a total of 524 patients met the inclusion criteria. The meta-analysis showed a significant difference in estimated blood loss between embolised and non-embolised groups (overall effect size -685 ml; p < 0.001). Additionally, embolised patients with advanced stage tumours tended to lose less blood during surgery than non-embolised patients (mean of 1551.9 ml vs. 4051.5 ml; p = 0.065).\n\nConclusion: This systematic review and meta-analysis demonstrate that pre-operative endovascular embolisation provides an operative advantage in patients undergoing juvenile nasopharyngeal angiofibroma surgical resection. A near-significant trend towards greater benefit in higher-stage tumours was observed (p = 0.065), warranting further prospective investigation.",
  "abstract_shown": true,
  "affiliations": [
    "Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel",
    "Department of Otolaryngology - Head and Neck Surgery, Galilee Medical Centre, Nahariya, Israel"
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Aviv Yvonne Segal"
    },
    {
      "affs": [
        0
      ],
      "name": "Basem Hijazi"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Ohad Ronen",
      "orcid": "0000-0001-7084-0695"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/e24ngze9m3z64.bib",
  "cited_by": 0,
  "doi": "10.1017/s0022215126104885",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13719260/",
  "id": "e24ngze9m3z64",
  "issns": [
    "0022-2151",
    "1748-5460"
  ],
  "landing_url": "https://doi.org/10.1017/s0022215126104885",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Review Article"
    ],
    [
      "openalex",
      "2746|Head and Neck Surgical Oncology"
    ]
  ],
  "openalex": "W7160445460",
  "pdf_url": null,
  "pmcid": "PMC13719260",
  "pmid": "42087760",
  "published": "2026-10-30",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/e24ngze9m3z64.ris",
  "sources": [
    {
      "first_seen": "2026-11-02T12:23:07Z",
      "native_id": "PMC13719260",
      "source": "pmc",
      "url": "https://doi.org/10.1017/s0022215126104885"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Head and Neck Surgical Oncology",
      "subfield": "surgery"
    }
  ],
  "title": "Operative benefits of embolisation in advanced-stage juvenile nasopharyngeal angiofibroma: a meta-analytic comparison",
  "title_text": "Operative benefits of embolisation in advanced-stage juvenile nasopharyngeal angiofibroma: a meta-analytic comparison",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:23:07Z",
  "url": "https://research.draconitic.com/paper/e24ngze9m3z64",
  "venue": "The Journal of Laryngology and Otology",
  "versions": []
}