{
  "abstract": "Whereas the etiology of non-alcoholic fatty liver disease (NAFLD) is complex, the role of nutrition as a causing and preventive factor is not fully explored. The aim of this study is to associate dietary patterns with magnetic resonance imaging (MRI) parameters in a European population (Greece, Italy, and Serbia) affected by NAFLD. For the first time, iron-corrected T1 (cT1), proton density fat fraction (PDFF), and the liver inflammation fibrosis score (LIF) were examined in relation to diet. A total of 97 obese patients with NAFLD from the MAST4HEALTH study were included in the analysis. A validated semi-quantitative food frequency questionnaire (FFQ) was used to assess the quality of diet and food combinations. Other variables investigated include anthropometric measurements, total type 2 diabetes risk, physical activity level (PAL), and smoking status. Principal component analysis (PCA) was performed to identify dietary patterns. Six dietary patterns were identified, namely “High-Sugar”, “Prudent”, “Western”, “High-Fat and Salt”, “Plant-Based”, and “Low-Fat Dairy and Poultry”. The “Western” pattern was positively associated with cT1 in the unadjusted model (beta: 0.020, p-value: 0.025) and even after adjusting for age, sex, body mass index (BMI), PAL, smoking, the center of the study, and the other five dietary patterns (beta: 0.024, p-value: 0.020). On the contrary, compared with low-intake patients, those with medium intake of the “Low-Fat Dairy and Poultry” pattern were associated with lower values of cT1, PDFF, and LIF. However, patients with a “Low-Fat Dairy and Poultry” dietary pattern were negatively associated with MRI parameters (cT1: beta: −0.052, p-value: 0.046, PDFF: beta: −0.448, p-value: 0.030, LIF: beta: −0.408, p-value: 0.025). Our findings indicate several associations between MRI parameters and dietary patterns in NAFLD patients, highlighting the importance of diet in NAFLD.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 22,
  "authors": [
    {
      "name": "Athina Amanatidou"
    },
    {
      "name": "Andriana Kaliora"
    },
    {
      "name": "Charalampia Amerikanou"
    },
    {
      "name": "Stefan Stojanoski"
    },
    {
      "name": "Natasa Milosevic"
    },
    {
      "name": "Chara Vezou"
    },
    {
      "name": "Mirjana Beribaka"
    },
    {
      "name": "Rajarshi Banerjee"
    },
    {
      "name": "Ioanna-Panagiota Kalafati"
    },
    {
      "name": "Ilias Smyrnioudis"
    },
    {
      "name": "Mary Jo Kurth"
    },
    {
      "name": "Aimo Kannt"
    },
    {
      "name": "M. Pilar Francino"
    },
    {
      "name": "Sophie Visvikis-Siest"
    },
    {
      "name": "Panos Deloukas"
    },
    {
      "name": "Carlos Llorens"
    },
    {
      "name": "Fernando Marascio"
    },
    {
      "name": "Natasa Milic"
    },
    {
      "name": "Milica Medic-Stojanoska"
    },
    {
      "name": "Amalia Gastaldelli"
    },
    {
      "name": "Maria Giovanna Trivella"
    },
    {
      "name": "George Dedoussis"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/e6dywvv9bk3m8.bib",
  "cited_by": 4,
  "doi": "10.3390/ijerph19020971",
  "fulltext_url": null,
  "id": "e6dywvv9bk3m8",
  "issns": [
    "1661-7827",
    "1660-4601"
  ],
  "landing_url": "https://hal.univ-lorraine.fr/hal-03527992v1",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "2713|Liver Disease Diagnosis and Treatment"
    ]
  ],
  "openalex": "W4205777256",
  "pdf_url": "https://hal.univ-lorraine.fr/hal-03527992/document",
  "pmcid": null,
  "pmid": "35055797",
  "published": "2026-09-03",
  "publisher": "MDPI",
  "ris": "https://research.draconitic.com/paper/e6dywvv9bk3m8.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:27Z",
      "native_id": "hal-03527992",
      "source": "hal",
      "url": "https://hal.univ-lorraine.fr/hal-03527992v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Liver Disease Diagnosis and Treatment",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Association of Dietary Patterns with MRI Markers of Hepatic Inflammation and Fibrosis in the MAST4HEALTH Study",
  "title_text": "Association of Dietary Patterns with MRI Markers of Hepatic Inflammation and Fibrosis in the MAST4HEALTH Study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:27Z",
  "url": "https://research.draconitic.com/paper/e6dywvv9bk3m8",
  "venue": "International Journal of Environmental Research and Public Health",
  "versions": []
}