{
  "abstract": "A 71-year-old man with Waldenström's macroglobulinemia developed probable Pneumocystis jirovecii pneumonia (PCP) 10 months after completing bendamustine-rituximab (BR) therapy and 7 months after discontinuing trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis. His CD4-positive T-cell count was 37 cells/μL, and no other apparent risk factors, including human immunodeficiency virus infection, were identified. While his condition improved with TMP-SMX, his CD4-positive T-cell count had only recovered to 183 cells/μL by 18 months after completing BR therapy. This case suggests that prolonged CD4-positive T-cell depletion after BR therapy may contribute to late-onset PCP and it highlights the importance of an individualized assessment of immune recovery and PCP prophylaxis.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "Haruka Zukeyama"
    },
    {
      "name": "Shuhei Ideguchi"
    },
    {
      "name": "Tomo Kiyuna"
    },
    {
      "name": "Kazutaka Yamaniha"
    },
    {
      "name": "Shosin Yamazato"
    },
    {
      "name": "Hideta Nakamura"
    },
    {
      "name": "Takeshi Kinjo"
    },
    {
      "name": "Makoto Furugen"
    },
    {
      "name": "Kazuya Miyagi"
    },
    {
      "name": "Kazuko Yamamoto"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/e6kk6t0bg6a9h.bib",
  "cited_by": 1,
  "doi": "10.2169/internalmedicine.7937-26",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7937-26/_article",
  "id": "e6kk6t0bg6a9h",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7937-26/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "2713|Pneumocystis jirovecii pneumonia detection and treatment"
    ]
  ],
  "openalex": "W7214631771",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7937-26/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-29",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/e6kk6t0bg6a9h.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "10.2169/internalmedicine.7937-26",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7937-26/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Pneumocystis jirovecii pneumonia detection and treatment",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Pneumocystis Jirovecii Pneumonia Associated with Prolonged CD4-positive T-cell Depletion after Bendamustine-Rituximab Therapy: A Case Report",
  "title_text": "Pneumocystis Jirovecii Pneumonia Associated with Prolonged CD4-positive T-cell Depletion after Bendamustine-Rituximab Therapy: A Case Report",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/e6kk6t0bg6a9h",
  "venue": "Internal Medicine",
  "versions": []
}