{
  "abstract": "Spiroligomers are rigid, stereochemically defined scaffolds that can be programmed to display functional groups in precise three-dimensional constellations. We utilize this scaffold to position two urea groups in a preorganized geometry for anion binding. Among the receptors synthesized, the spiroligomer with RRRR-configuration displayed the strongest affinity for hydrogen pyrophosphate H2PPi (H2P2O7",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "name": "Yanfeng Fan"
    },
    {
      "name": "Kyle Brunner",
      "orcid": "0009-0007-2417-539X"
    },
    {
      "name": "Chongsong Xu"
    },
    {
      "name": "Owen O’Sullivan"
    },
    {
      "name": "Melody Pham"
    },
    {
      "name": "Michael J. Zdilla"
    },
    {
      "name": "Christian E. Schafmeister"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/e794bcfb6g1th.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15007885/v2",
  "fulltext_url": null,
  "id": "e794bcfb6g1th",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15007885/v2",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Supramolecular Chemistry and Complexes"
    ]
  ],
  "openalex": "W7213357728",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-14",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/e794bcfb6g1th.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:19Z",
      "native_id": "10.26434/chemrxiv.15007885",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15007885/v2"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Supramolecular Chemistry and Complexes",
      "subfield": "organic"
    }
  ],
  "title": "The Design and Application of Diureido Functionalized Spiroligomers as Diphosphate Receptors",
  "title_text": "The Design and Application of Diureido Functionalized Spiroligomers as Diphosphate Receptors",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:19Z",
  "url": "https://research.draconitic.com/paper/e794bcfb6g1th",
  "venue": "ChemRxiv",
  "versions": []
}