{
  "abstract": "ObjectivesTo evaluate change in physical function and probable sarcopenia following a 36-week community multicomponent exercise programme (Vivifrail model) across two consecutive cycles, and to assess the consistency of this change between cohorts.\n\nStudy designQuasi-experimental, single-arm, repeated-measures service evaluation. Ninety-two older adults (2025-2026 cohort; mean age 75.9 years, 88.0% women) completed baseline and post-intervention assessments; an independent 2024-2025 cohort (n = 86) was analysed jointly for replication (n = 178).\n\nMain outcome measuresShort Physical Performance Battery (SPPB) score (primary); Timed Up and Go (TUG), handgrip strength, 6-metre walk time and Mini-Mental State Examination (MMSE) (secondary); probable sarcopenia (EWGSOP2), SPPB-based frailty category, and a fall-risk indicator computed identically in both cohorts.\n\nResultsSPPB improved by a mean of 1.33 points (Cohens d = 0.96; p < .001), with concordant improvement in all four secondary outcomes (all q < .005). 72.8% reached the substantial minimal clinically important difference. Probable sarcopenia fell from 17.4% to 5.4% (p = .006), and frailty category shifted toward higher functional levels (p < .001). Effect sizes were consistent between cohorts for SPPB, handgrip and 6-metre walk; the TimexCohort interaction was significant for TUG only. In the pooled sample, elevated fall risk fell from 19.7% to 11.2% (p = .002).\n\nConclusionsA 36-week multicomponent exercise programme was associated with clinically meaningful, reproducible improvement in physical function and a reduction in probable sarcopenia across two independent cohorts. The single-arm design precludes causal inference.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada,"
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "J. Fernandez-Ortega"
    },
    {
      "name": "J. Loza-Herbella"
    },
    {
      "name": "J. A. Rangel-Garcia"
    },
    {
      "name": "A. B. Fernandez-Revelles"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/eawbwz7v5d1qy.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.10.14.26365508",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.10.14.26365508v1.full",
  "id": "eawbwz7v5d1qy",
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  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.10.14.26365508v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "geriatric medicine"
    ],
    [
      "openalex",
      "2737|Nutrition and Health in Aging"
    ]
  ],
  "openalex": "W7222497091",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.10.14.26365508v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-14",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/eawbwz7v5d1qy.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:04Z",
      "native_id": "10.64898/2026.10.14.26365508",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.10.14.26365508v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2737|Nutrition and Health in Aging",
      "subfield": "physiology"
    }
  ],
  "title": "Restoring Physical Resilience: Consistent Functional and Sarcopenia Gains Across Two Vivifrail Cohorts",
  "title_text": "Restoring Physical Resilience: Consistent Functional and Sarcopenia Gains Across Two Vivifrail Cohorts",
  "type": "preprint",
  "updated_at": "2026-10-30T12:21:04Z",
  "url": "https://research.draconitic.com/paper/eawbwz7v5d1qy",
  "venue": "medRxiv",
  "versions": []
}