{
  "abstract": "Preliminary analysis of genomic surveillance data from the European Antimicrobial Resistance Gene Surveillance Network detected the spread of the emerging carbapenemase-producing Klebsiella pneumoniae sequence type ST6668 in 19 NUTS-2 regions in Italy (8 regions) and five other European Union (EU) countries (11 regions) in the period April 2022 to August 2026. These findings demonstrate the vulnerability of EU healthcare facilities to the rapid spread of K. pneumoniae high-risk lineages from uncontrolled local outbreaks via national and cross-border patient mobility.",
  "abstract_shown": true,
  "affiliations": [
    "National Reference Laboratory for Antimicrobial Resistance, Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy",
    "European Centre for Disease Prevention and Control, Solna, Sweden",
    "Core Facilities Technical-Scientific Service, Istituto Superiore di Sanità, Rome, Italy",
    "National Reference Laboratory for Antimicrobial Resistance, Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark",
    "European Union Reference Laboratory for Public Health on Antimicrobial Resistance in Bacteria (EURL-PH-AMR), Copenhagen, Denmark",
    "French National Reference Center for Antibiotic Resistance, Le Kremlin-Bicêtre, France",
    "Team 'Resist' UMR1184 'Immunology of Viral, Auto-Immune, Hematological and Bacterial Diseases (IMVA-HB)', INSERM, Université Paris-Saclay, CEA, LabEx LERMIT, Le Kremlin-Bicêtre Cedex, France",
    "Department of Bacteriology-Hygiene, Bicêtre Hospital, Assistance Publique-Hôpitaux de Paris, Le Kremlin-Bicêtre, France",
    "Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany",
    "German National Reference Centre for Multidrug-resistant Gram-negative Bacteria, Department of Medical Microbiology, Ruhr-University Bochum, Bochum, Germany",
    "Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands",
    "Carol Davila University of Medicine and Pharmacy, Bucharest, Romania",
    "National Institute for Infectious Disease “Prof. Dr. Matei Balş”, Bucharest, Romania",
    "The members of the Italian CRE25 survey working group for Klebsiella pneumoniae ST6668 are listed under Collaborators and at the end of the article."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 36,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Giulia Errico",
      "orcid": "0000-0001-9151-0652"
    },
    {
      "affs": [
        1
      ],
      "name": "Marius Linkevicius",
      "orcid": "0000-0001-5760-2721"
    },
    {
      "affs": [
        0
      ],
      "name": "Alessandra Lo Sciuto"
    },
    {
      "affs": [
        0
      ],
      "name": "Cristiana Barbati",
      "orcid": "0000-0003-4121-5342"
    },
    {
      "affs": [
        0
      ],
      "name": "Sara Giancristofaro",
      "orcid": "0009-0006-4678-2062"
    },
    {
      "affs": [
        2
      ],
      "name": "Manuela Marra",
      "orcid": "0000-0001-9710-118X"
    },
    {
      "affs": [
        2
      ],
      "name": "Valentina Libri",
      "orcid": "0000-0002-2080-1089"
    },
    {
      "affs": [
        0
      ],
      "name": "Maria Del Grosso",
      "orcid": "0000-0002-2663-9764"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Anette M Hammerum",
      "orcid": "0000-0001-9471-1601"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Louise Roer",
      "orcid": "0000-0001-6892-913X"
    },
    {
      "affs": [
        5,
        6,
        7
      ],
      "name": "Rémy A Bonnin",
      "orcid": "0000-0002-2307-3232"
    },
    {
      "affs": [
        5,
        6,
        7
      ],
      "name": "Laurent Dortet",
      "orcid": "0000-0001-6596-7384"
    },
    {
      "affs": [
        8
      ],
      "name": "Felix Reichert",
      "orcid": "0000-0003-3205-3513"
    },
    {
      "affs": [
        9
      ],
      "name": "Lisa-Marie Höfken",
      "orcid": "0009-0003-3108-5529"
    },
    {
      "affs": [
        10
      ],
      "name": "Antoni PA Hendrickx",
      "orcid": "0000-0003-4431-9323"
    },
    {
      "affs": [
        11,
        12
      ],
      "name": "Dragos Florea",
      "orcid": "0000-0001-7328-6861"
    },
    {
      "affs": [
        11,
        12
      ],
      "name": "Daniela Talapan",
      "orcid": "0000-0001-5202-8417"
    },
    {
      "affs": [
        1
      ],
      "name": "Erik Alm",
      "orcid": "0000-0002-2903-607X"
    },
    {
      "affs": [
        1
      ],
      "name": "Olov Svartström",
      "orcid": "0000-0003-3100-5325"
    },
    {
      "affs": [
        1
      ],
      "name": "Priyanka Nannapaneni",
      "orcid": "0000-0003-2629-4249"
    },
    {
      "affs": [
        1
      ],
      "name": "Anke Kohlenberg",
      "orcid": "0009-0001-6322-9844"
    },
    {
      "affs": [
        0
      ],
      "name": "Monica Monaco",
      "orcid": "0000-0002-6628-1621"
    },
    {
      "affs": [
        13
      ],
      "name": "the Italian CRE25 survey working group for Klebsiella pneumoniae ST6668"
    },
    {
      "name": "Collaborators"
    },
    {
      "name": "Claudio Giacomazzi"
    },
    {
      "name": "Marisa Accogli"
    },
    {
      "name": "Maria Chironna"
    },
    {
      "name": "Floriana Gona"
    },
    {
      "name": "Maddalena Calvo"
    },
    {
      "name": "Stefania Stefani"
    },
    {
      "name": "Francesca Greco"
    },
    {
      "name": "Chiara Vismara"
    },
    {
      "name": "Teresa Lopizzo"
    },
    {
      "name": "Sofia Chiatamone Ranieri"
    },
    {
      "name": "Annarita Mazzariol"
    },
    {
      "name": "Luciano Castiello"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/edah49k18avby.bib",
  "cited_by": 0,
  "doi": "10.2807/1560-7917.es.2026.31.43.2600861",
  "fulltext_url": "https://europepmc.org/articles/PMC13722929",
  "id": "edah49k18avby",
  "issns": [
    "1025-496X",
    "1560-7917"
  ],
  "landing_url": "https://europepmc.org/article/MED/42960468",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Rapid Communication"
    ],
    [
      "openalex",
      "1313|Antibiotic Resistance in Bacteria"
    ]
  ],
  "openalex": "W7224895252",
  "pdf_url": "https://europepmc.org/articles/PMC13722929?pdf=render",
  "pmcid": "PMC13722929",
  "pmid": "42960468",
  "published": "2026-10-01",
  "publisher": "European Centre for Disease Prevention and Control",
  "ris": "https://research.draconitic.com/paper/edah49k18avby.ris",
  "sources": [
    {
      "first_seen": "2026-11-02T03:21:43Z",
      "native_id": "MED:42960468",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42960468"
    },
    {
      "first_seen": "2026-11-04T12:21:38Z",
      "native_id": "PMC13722929",
      "source": "pmc",
      "url": "https://doi.org/10.2807/1560-7917.es.2026.31.43.2600861"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:1313|Antibiotic Resistance in Bacteria",
      "subfield": "general"
    }
  ],
  "title": "Rapid inter-regional and cross-border dissemination of carbapenemase-producing Klebsiella pneumoniae ST6668, European Union, April 2022 to August 2026.",
  "title_text": "Rapid inter-regional and cross-border dissemination of carbapenemase-producing Klebsiella pneumoniae ST6668, European Union, April 2022 to August 2026.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-04T12:21:38Z",
  "url": "https://research.draconitic.com/paper/edah49k18avby",
  "venue": "Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin",
  "versions": []
}