{
  "abstract": "Objective: This study aimed to investigate the association of an Online Co-care Management (OCCM) model with changes in glycemic control and metabolic indicators among patients with type 2 diabetes mellitus (T2DM). Methods: Based on clinical follow-up records, we conducted a retrospective cohort study with a propensity score (PS)-matched control group.The OCCM group included patients enrolled in the integrated care clinic from 2022 to 2025 (n = 406). Among patients who did not participate in OCCM (n = 199) during the study period, PS-matched controls were selected at a 1:1 ratio.The PS model included age, sex, diabetes duration, smoking, drinking, medication use, and follow-up duration.After matching, 240 patients were included in the final analysis, with 120 patients in each group. Follow-up data were collected at baseline, 3 months, and 6 months. Longitudinal data on anthropometrics, glycemic indices, blood pressure, lipid profiles, and organ function were analyzedusing repeated measures ANOVA. Results: Over a 6-month follow-up period, HbA1c levels decreased more markedly in the OCCM group compared with the usual-care group. In the OCCM group, HbA1c declined from 7.403 ± 1.748% at baseline to 6.591 ± 0.871% at 3 months and 6.593 ± 1.056% at 6 months, while in the usual-care group, it changed from 6.310 ± 1.277% to 6.225 ± 1.017% and 6.534 ± 1.598%, respectivelyRepeated-measures ANOVA revealed significant time, group, and time × group effects for HbA1c (F = 10.608, P < 0.001; F = 16.748, P < 0.001; F = 14.546, P < 0.001). BMI, systolic and diastolic blood pressure, and lipid profiles, also showed greater improvements in the OCCM group than in controls. Conclusion: The OCCM model was associated with short-term improvements in glycemic and metabolic indicators among T2DM patients, suggesting it may be an effective approach for structured chronic disease management.",
  "abstract_shown": true,
  "affiliations": [
    "General Practice Department, Wanshou Road Community Health Service Center of Haidian District, Beijing, China.",
    "Department of Clinical Nutrition, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.",
    "Department of Traditional Chinese Medicine, Air Force Medical Center PLA, Beijing, China.",
    "General Practice Department, Air Force Medical Center PLA, Beijing, China."
  ],
  "article_type": "Research Article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Shujuan Sun"
    },
    {
      "affs": [
        1
      ],
      "name": "Ge Yang"
    },
    {
      "affs": [
        2
      ],
      "name": "Hao Tong",
      "orcid": "0009-0008-0278-911X"
    },
    {
      "affs": [
        0
      ],
      "name": "Hui Zhao"
    },
    {
      "affs": [
        0
      ],
      "name": "Qin Liu"
    },
    {
      "affs": [
        0
      ],
      "name": "Yiran He"
    },
    {
      "affs": [
        3
      ],
      "name": "Zhiyue Zhang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/eh5m3k8cwf54t.bib",
  "cited_by": 0,
  "doi": "10.1371/journal.pone.0360677",
  "fulltext_url": "https://europepmc.org/articles/PMC13726964",
  "id": "eh5m3k8cwf54t",
  "issns": [
    "1932-6203"
  ],
  "landing_url": "https://doi.org/10.1371/journal.pone.0360677",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Biochemistry"
    ],
    [
      "heading",
      "Biology and Life Sciences"
    ],
    [
      "heading",
      "Biology and life sciences"
    ],
    [
      "heading",
      "Blood Pressure"
    ],
    [
      "heading",
      "Cholesterol"
    ],
    [
      "heading",
      "Diabetes Mellitus"
    ],
    [
      "heading",
      "Diabetes diagnosis and management"
    ],
    [
      "heading",
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    ],
    [
      "heading",
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    ],
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      "heading",
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      "heading",
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      "heading",
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  "pdf_url": "https://europepmc.org/articles/PMC13726964?pdf=render",
  "pmcid": "PMC13726964",
  "pmid": "42970553",
  "published": "2026-11-02",
  "publisher": "Public Library of Science",
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  "subjects": [
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      "field": "biochemistry",
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  "title": "Online co-care management and glycemic control in patients with type 2 diabetes mellitus: A propensity score-matched retrospective cohort study",
  "title_text": "Online co-care management and glycemic control in patients with type 2 diabetes mellitus: A propensity score-matched retrospective cohort study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:22:47Z",
  "url": "https://research.draconitic.com/paper/eh5m3k8cwf54t",
  "venue": "PLOS One",
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}