{
  "abstract": "Hemodiafiltration (HDF) combines diffusive and convective clearance, enhancing the removal of uremic toxins, particularly middle molecules, compared with conventional hemodialysis (HD). Recent evidence, including meta-analyses and the CONVINCE trial, suggests that high-volume HDF is associated with improved clinical outcomes, particularly when adequate convective volumes are achieved. In Brazil, the expansion of this modality has been accompanied by studies demonstrating its feasibility, safety, and applicability across different clinical settings. This position statement from the Brazilian Society of Nephrology (SBN), educational rather than normative in nature, provides recommendations based on the best available evidence and expert consensus regarding the use of HDF in maintenance dialysis in Brazil. The document addresses patient selection, minimum prescription parameters, operational targets, technical and safety requirements, as well as ethical, regulatory, and economic aspects, with the aim of supporting clinical and managerial decision-making, reducing practice variability, and promoting safer, higher-quality dialysis care.",
  "abstract_shown": true,
  "affiliations": [
    "Brazilian Society of Nephrology, São Paulo, SP, Brazil.",
    "Hospital de Base-FUNFARME, São José do Rio Preto, SP, Brazil.",
    "Universidade de São Paulo, São Paulo, SP, Brazil.",
    "Universidade Nove de Julho, São Paulo, SP, Brazil.",
    "Fundação Hospital de Clínicas Gaspar Vianna, Belém, PA, Brazil.",
    "Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.",
    "Instituto de Doenças Renais, Porto Alegre, RS, Brazil.",
    "Universidade do Vale do Rio dos Sinos, São Leopoldo, RS, Brazil.",
    "Secretaria de Saúde do Estado de São Paulo, São Paulo, SP, Brazil.",
    "Instituto Dante Pazzanese de Cardiologia, São Paulo, SP, Brazil.",
    "Karolinska Institutet, Department of Clinical Science, Intervention and Technology, Division of Renal Medicine, Stockholm, Sweden.",
    "VIVATUM PD AG, Eschenbach, Switzerland.",
    "Vicenza International Institute of Kidney Research, Vicenza, Italia.",
    "Universidade Federal da Bahia, Programa de Pós-Graduação em Ciências da Saúde, Salvador, BA, Brazil.",
    "Santa Casa de Belo Horizonte, Unidade de Nefrologia Pediátrica, Belo Horizonte, MG, Brazil.",
    "Universidade Federal de Minas Gerais, Faculdade de Medicina, Belo Horizonte, MG, Brazil.",
    "Universidade Federal de São Paulo, São Paulo, SP, Brazil.",
    "Hospital São João de Deus, Divinópolis, MG, Brazil.",
    "Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Instituto da Criança, São Paulo, SP, Brazil.",
    "Faculdade Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 15,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Fernanda Salomão Gorayeb-Polacchini",
      "orcid": "0000-0001-8803-1300"
    },
    {
      "affs": [
        0,
        2,
        3
      ],
      "name": "Rosilene Motta Elias",
      "orcid": "0000-0003-2212-041X"
    },
    {
      "affs": [
        0,
        4
      ],
      "name": "Ana Lydia Lédo de Castro Ribeiro Cabeça",
      "orcid": "0000-0001-5381-0400"
    },
    {
      "affs": [
        0,
        5,
        6,
        7
      ],
      "name": "Dirceu Reis da Silva",
      "orcid": "0000-0002-7587-0604"
    },
    {
      "affs": [
        0
      ],
      "name": "Elizabeth Machado",
      "orcid": "0009-0008-9288-7855"
    },
    {
      "affs": [
        0,
        8,
        9
      ],
      "name": "Farid Samaan",
      "orcid": "0000-0003-4393-7330"
    },
    {
      "affs": [
        0
      ],
      "name": "Isadora Cartaxo de Sousa Calvo",
      "orcid": "0009-0008-5436-5976"
    },
    {
      "affs": [
        10,
        11
      ],
      "name": "José Carolino Divino Filho",
      "orcid": "0000-0002-6705-9408"
    },
    {
      "affs": [
        0
      ],
      "name": "Kalyanne Cabral de Paula do Ó",
      "orcid": "0000-0001-7115-2683"
    },
    {
      "affs": [
        0,
        12,
        13
      ],
      "name": "Maria Gabriela Motta Guimarães",
      "orcid": "0000-0001-8500-0218"
    },
    {
      "affs": [
        0,
        14,
        15
      ],
      "name": "Maria Goretti Moreira Guimarães Penido",
      "orcid": "0000-0002-1534-3861"
    },
    {
      "affs": [
        0,
        16
      ],
      "name": "Patrícia Ferreira Abreu",
      "orcid": "0009-0007-9860-4812"
    },
    {
      "affs": [
        0,
        17
      ],
      "name": "Stenio Barbosa de Freitas",
      "orcid": "0000-0002-0440-2686"
    },
    {
      "affs": [
        0,
        18
      ],
      "name": "Vera Hermina Kalika Koch",
      "orcid": "0000-0001-7478-3931"
    },
    {
      "affs": [
        0,
        19
      ],
      "name": "José A Moura-Neto",
      "orcid": "0000-0003-1339-3731"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ej7ztzwmnz3mj.bib",
  "cited_by": 0,
  "doi": "10.1590/2175-8239-jbn-2026-0161en",
  "fulltext_url": "https://europepmc.org/articles/PMC13660142",
  "id": "ej7ztzwmnz3mj",
  "issns": [
    "0101-2800",
    "2175-8239"
  ],
  "landing_url": "https://europepmc.org/article/MED/42837114",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2727|Dialysis and Renal Disease Management"
    ]
  ],
  "openalex": "W7220384266",
  "pdf_url": "https://europepmc.org/articles/PMC13660142?pdf=render",
  "pmcid": "PMC13660142",
  "pmid": "42837114",
  "published": "2026-10-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/ej7ztzwmnz3mj.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:10Z",
      "native_id": "MED:42837114",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42837114"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2727|Dialysis and Renal Disease Management",
      "subfield": "general"
    }
  ],
  "title": "Recommendations of the Brazilian Society of Nephrology for hemodiafiltration in maintenance dialysis therapy.",
  "title_text": "Recommendations of the Brazilian Society of Nephrology for hemodiafiltration in maintenance dialysis therapy.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:10Z",
  "url": "https://research.draconitic.com/paper/ej7ztzwmnz3mj",
  "venue": "Jornal brasileiro de nefrologia",
  "versions": []
}