{
  "abstract": "iInferring coalescent trees from genomic data has become a major subject in population genetics, particularly with the recent advances in tree sequence reconstruction methods. Yet, how well these methods perform under imbalanced genealogies remains unclear. Such imbalances can arise from processes such as cultural transmission of reproductive success (CTRS) or positive selection. Using simulated genomic data, we benchmarked two major software packages, Relate and tsinfer, by comparing the imbalance of reconstructed trees by these methods with that of the true simulated trees, for three indices that quantify this imbalance. Both methods performed well under scenarios yielding balanced trees. However, their accuracy declined as imbalance increased. Performances also varied with mutation rate, recombination rate, and sample size. This study opens possibilities for applying these methods to infer CTRS or positive selection in large-scale genomic datasets, using simulation-based inference such as approximate Bayesian computation.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "name": "Fanny Pouyet"
    },
    {
      "name": "Ferdinand Petit"
    },
    {
      "name": "Jérémy Guez"
    },
    {
      "name": "Léo Planche"
    },
    {
      "name": "Evelyne Heyer"
    },
    {
      "name": "Bruno Toupance"
    },
    {
      "name": "Flora Jay"
    },
    {
      "name": "Frédéric Austerlitz"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/enw6420aavbbb.bib",
  "cited_by": 0,
  "doi": "10.1093/gbe/evag215",
  "fulltext_url": null,
  "id": "enw6420aavbbb",
  "issns": [
    "1759-6653",
    "1759-6653"
  ],
  "landing_url": "https://cnrs.hal.science/hal-05347078v2",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "hal",
      "1.sdv.gen"
    ],
    [
      "hal",
      "2.sdv.gen.gpo"
    ],
    [
      "openalex",
      "1311|Genetic diversity and population structure"
    ]
  ],
  "openalex": "W7204163009",
  "pdf_url": "https://cnrs.hal.science/hal-05347078/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-26",
  "publisher": "Society for Molecular Biology and Evolution",
  "ris": "https://research.draconitic.com/paper/enw6420aavbbb.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:56Z",
      "native_id": "hal-05347078",
      "source": "hal",
      "url": "https://cnrs.hal.science/hal-05347078v2"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:1.sdv.gen",
      "subfield": "genetics-genomics"
    }
  ],
  "title": "Comparing ARG inference methods under transmission of reproductive success: Tree imbalance matters",
  "title_text": "Comparing ARG inference methods under transmission of reproductive success: Tree imbalance matters",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:56Z",
  "url": "https://research.draconitic.com/paper/enw6420aavbbb",
  "venue": "Genome Biology and Evolution",
  "versions": []
}