{
  "abstract": "Long-term outcomes after kidney re-transplantation in patients with childhood-onset kidney replacement therapy (KRT) are poorly characterized. Using European Renal Association Registry data, we studied 12,623 patients who started KRT before age 20 years and received one (n = 11,078), two (n = 2,962) or three (n = 718) kidney transplants (KTs) between 1978 and 2019. In this descriptive study, 5-, 10- and 15-year patient survival was 97, 94 and 90 % after first, 97, 95, 94 % after second and 96, 94, 92 % after third KT; corresponding graft survival was 79, 63, 50 %, 69, 52, 38 %, and 67, 51, 38 %, respectively. After first KT, mortality and graft failure risks were lower after pre-emptive transplantation (adjusted hazard ratio: 0.66 [95% CI 0.54-0.80] and 0.89 [0.82-0.97], respectively) and after living donor (LD) transplantation (0.71 [0.61-0.83] and 0.76 [0.70-0.81], respectively). Additionally, graft failure risk was higher between ages 10-24 years, and for patients with glomerulonephritis, metabolic diseases or recurrent nephropathies, and females. In re-transplants, LD and pre-emptive KTs (particularly for second KT) and prior graft survival > 5 years were associated with reduced graft failure. Overall, LD, pre-emptive transplantation, and durable prior grafts were associated with the best outcomes.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 21,
  "authors": [
    {
      "name": "Jelena Stojanovic"
    },
    {
      "name": "Søren S. Sørensen"
    },
    {
      "name": "Ann Christin Gjerstad"
    },
    {
      "name": "María Herrero-Goñi"
    },
    {
      "name": "Olga Lucía Rodriguez Arévalo"
    },
    {
      "name": "Michel Tsimaratos"
    },
    {
      "name": "Viktorija Kuzema"
    },
    {
      "name": "Mårten Segelmark"
    },
    {
      "name": "Runolfur Palsson"
    },
    {
      "name": "Alberto Ortiz"
    },
    {
      "name": "Kitty J. Jager"
    },
    {
      "name": "Jérôme Harambat"
    },
    {
      "name": "Evgenia Preka"
    },
    {
      "name": "Marjolein Bonthuis"
    },
    {
      "name": "Stephen D. Marks"
    },
    {
      "name": "Anneke Kramer"
    },
    {
      "name": "Vianda S. Stel"
    },
    {
      "name": "Lukas Buchwinkler"
    },
    {
      "name": "Belén Ponte"
    },
    {
      "name": "Anders Åsberg"
    },
    {
      "name": "Stella Stabouli"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ep5kwe6q961e2.bib",
  "cited_by": 0,
  "doi": "10.1016/j.ajt.2026.10.017",
  "fulltext_url": null,
  "id": "ep5kwe6q961e2",
  "issns": [
    "1600-6135",
    "1600-6143"
  ],
  "landing_url": "https://hal.science/hal-05858055v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "hal",
      "1.sdv.spee"
    ],
    [
      "openalex",
      "2747|Renal Transplantation Outcomes and Treatments"
    ]
  ],
  "openalex": "W7224137703",
  "pdf_url": "https://www.amjtransplant.org/article/S1600-6135(26)02852-2/pdf",
  "pmcid": null,
  "pmid": "42951115",
  "published": "2026-11-09",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/ep5kwe6q961e2.ris",
  "sources": [
    {
      "first_seen": "2026-11-10T12:20:54Z",
      "native_id": "hal-05858055",
      "source": "hal",
      "url": "https://hal.science/hal-05858055v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    },
    {
      "field": "medicine",
      "origin": "hal:1.sdv.spee",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Long-Term Patient and Graft Survival for Children and Young Adults after Kidney Transplantation and Re-Transplantation - Results from the ERA Registry",
  "title_text": "Long-Term Patient and Graft Survival for Children and Young Adults after Kidney Transplantation and Re-Transplantation - Results from the ERA Registry",
  "type": "peer-reviewed",
  "updated_at": "2026-11-10T12:20:54Z",
  "url": "https://research.draconitic.com/paper/ep5kwe6q961e2",
  "venue": "American Journal of Transplantation",
  "versions": []
}