{
  "abstract": "Introduction and importance:: As clinicians strive to provide personalized recommendations for patients, polypseudophakia may be an option for those outside the range of traditional extended depth-of-focus lenses. We describe a case with initial refractive success but the development of a potentially vision-threatening complication.\n\nPresentation of case:: A 40-year-old Asian man with high myopia presented for a refractive surgery consultation with a goal of total spectacle independence and underwent bilateral refractive lens exchange with the J&J Synergy lens in the capsular bag, and a minus-power Alcon MA60MA lens in the sulcus. Initially, there was refractive success with post-operative uncorrected distance vision of 20/20 in the right eye and 20/25 in the left eye at 6 months. However, both eyes developed transillumination defects with pigment in the anterior chamber, consistent with Uveitis-Glaucoma-Hyphema (UGH) syndrome. The patient ultimately elected bilateral explantation of the sulcus intraocular lenses (IOLs) due to this complication.\n\nClinical discussion:: To our knowledge, this is the first case using the J&J Synergy lens in polypseudophakia and the second to correct for high myopia. Surgical techniques for those with high myopia and thin corneas are rare, and this technique initially provided a hopeful refractive outlook. However, loss of the refractive target and the development of UGH syndrome challenged the safety of this technique.\n\nConclusion:: Further studies are needed to determine which patients can tolerate this procedure. Providers should proceed cautiously and anticipate complications such as UGH syndrome following secondary sulcus IOL placement.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Ophthalmology, Loma Linda University School of Medicine, Loma Linda, CA, USA",
    "Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA",
    "Department of Ophthalmology, Loma Linda University Eye Institute, Loma Linda, CA, USA"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "David Durgan",
      "orcid": "0009-0001-3026-9452"
    },
    {
      "affs": [
        0
      ],
      "name": "Noah Collins"
    },
    {
      "affs": [
        1
      ],
      "name": "Jessica Kim"
    },
    {
      "affs": [
        2
      ],
      "name": "Frank Hwang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/eqaf5pebb5b0j.bib",
  "cited_by": 0,
  "doi": "10.1097/rc9.0000000000001076",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13747398/",
  "id": "eqaf5pebb5b0j",
  "issns": [
    "2210-2612"
  ],
  "landing_url": "https://doi.org/10.1097/rc9.0000000000001076",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2731|Intraocular Surgery and Lenses"
    ]
  ],
  "openalex": "W7224770769",
  "pdf_url": "https://europepmc.org/articles/PMC13747398?pdf=render",
  "pmcid": "PMC13747398",
  "pmid": "43006000",
  "published": "2026-10-14",
  "publisher": "Wolters Kluwer Health",
  "ris": "https://research.draconitic.com/paper/eqaf5pebb5b0j.ris",
  "sources": [
    {
      "first_seen": "2026-11-12T12:23:27Z",
      "native_id": "PMC13747398",
      "source": "pmc",
      "url": "https://doi.org/10.1097/rc9.0000000000001076"
    },
    {
      "first_seen": "2026-11-12T15:22:43Z",
      "native_id": "MED:43006000",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/43006000"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2731|Intraocular Surgery and Lenses",
      "subfield": "general"
    }
  ],
  "title": "Polypseudophakia with the J&J synergy lens in high myopia: case report",
  "title_text": "Polypseudophakia with the J&J synergy lens in high myopia: case report",
  "type": "peer-reviewed",
  "updated_at": "2026-11-13T12:24:17Z",
  "url": "https://research.draconitic.com/paper/eqaf5pebb5b0j",
  "venue": "International Journal of Surgery Case Reports",
  "versions": []
}