{
  "abstract": "Overwhelming post-splenectomy infection is a life-threatening condition typically caused by Streptococcus pneumoniae. Necrotizing fasciitis is a rare manifestation of invasive pneumococcal disease. A 73-year-old woman with a history of living-donor liver transplantation and splenectomy for primary biliary cholangitis presented with bilateral leg swelling, pain and altered consciousness. S. pneumoniae serotype 7C, sequence type 2758, was isolated from the blood and wound cultures. Despite intensive care and surgery, the patient developed liver graft failure and died on day 42. The emergence of non-vaccine serotypes highlights the urgent need for next-generation vaccines that target emerging strains.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "Hidemasa Akazawa"
    },
    {
      "name": "Shinnosuke Fukushima"
    },
    {
      "name": "Kenta Nakamoto"
    },
    {
      "name": "Kohei Oguni"
    },
    {
      "name": "Bin Chang"
    },
    {
      "name": "Yukihiro Akeda"
    },
    {
      "name": "Satoru Sugihara"
    },
    {
      "name": "Miyu Takenaka"
    },
    {
      "name": "Shin Morizane"
    },
    {
      "name": "Hideharu Hagiya"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/eqbe1ssajgz19.bib",
  "cited_by": 0,
  "doi": "10.2169/internalmedicine.6637-25",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/15/65_6637-25/_article",
  "id": "eqbe1ssajgz19",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/15/65_6637-25/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "2713|Pneumonia and Respiratory Infections"
    ]
  ],
  "openalex": "W4417209165",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_6637-25/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/eqbe1ssajgz19.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "10.2169/internalmedicine.6637-25",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/15/65_6637-25/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Pneumonia and Respiratory Infections",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Necrotizing Fasciitis Caused by Serotype 7C Streptococcus pneumoniae in Overwhelming Post-splenectomy Infection",
  "title_text": "Necrotizing Fasciitis Caused by Serotype 7C Streptococcus pneumoniae in Overwhelming Post-splenectomy Infection",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/eqbe1ssajgz19",
  "venue": "Internal Medicine",
  "versions": []
}