{
  "abstract": "The linear scaling relationships between multiple intermediates constrain catalytic performance, especially in single-atom catalysts (SACs) with isolated sites. This review focuses on overcoming this limitation by constructing SACs-based cooperative systems that exploit the directional spillover of key intermediates between functionally distinct sites. We systematically summarize how hydrogen-, oxygen-, carbon-, and nitrogen intermediates spillover between four representative cooperation paradigms, including multi-center SACs, SACs-nanoparticle hybrids, SACs-support interaction, and single-atom alloys. Through functional decoupling and site-to-site relay, these strategies reduce kinetic barriers of rate-determining steps and reconstruct reaction pathways. Beyond mitigating activity-selectivity-stability trade-offs of SACs, intermediate spillover mechanism moves catalyst design from trial-and-error approaches toward mechanism-guided engineering.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "name": "Minqi Shan"
    },
    {
      "name": "Jinliang Yuan"
    },
    {
      "name": "Tianyu Zhang",
      "orcid": "0000-0002-1250-9395"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/etbe4khj7j3jq.bib",
  "cited_by": 0,
  "doi": "10.1038/s42004-026-02158-5",
  "fulltext_url": "https://europepmc.org/articles/PMC13720144",
  "id": "etbe4khj7j3jq",
  "issns": [
    "2399-3669"
  ],
  "landing_url": "https://www.nature.com/articles/s42004-026-02158-5",
  "language": "eng",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Review Article"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.nature.com/articles/s42004-026-02158-5.pdf",
  "pmcid": "PMC13720144",
  "pmid": "42957806",
  "published": "2026-10-28",
  "publisher": "Springer Science and Business Media LLC",
  "ris": "https://research.draconitic.com/paper/etbe4khj7j3jq.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:20Z",
      "native_id": "10.1038/s42004-026-02158-5",
      "source": "feed-nature",
      "url": "https://www.nature.com/articles/s42004-026-02158-5"
    },
    {
      "first_seen": "2026-10-30T12:17:51Z",
      "native_id": "10.1038/s42004-026-02158-5",
      "source": "crossref",
      "url": "https://www.nature.com/articles/s42004-026-02158-5"
    },
    {
      "first_seen": "2026-11-01T00:20:36Z",
      "native_id": "MED:42957806",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42957806"
    },
    {
      "first_seen": "2026-11-02T12:23:59Z",
      "native_id": "PMC13720144",
      "source": "pmc",
      "url": "https://doi.org/10.1038/s42004-026-02158-5"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "issn:2399-3669",
      "subfield": "general"
    }
  ],
  "title": "Intermediate spillover-enabled cooperation in single-atom catalysts",
  "title_text": "Intermediate spillover-enabled cooperation in single-atom catalysts",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:21:05Z",
  "url": "https://research.draconitic.com/paper/etbe4khj7j3jq",
  "venue": "Communications Chemistry",
  "versions": []
}