{
  "abstract": "Coronavirus disease 2019 (COVID-19) presents with diagnostic and therapeutic challenges in immunocompromised patients, particularly those receiving anti-CD20 antibody therapy. This report describes a patient with recurrent pneumonia following COVID-19 after receiving anti-CD20 antibody therapy. Two transbronchial lung cryobiopsies documented active lung injury in two clinically distinct episodes. Based on an integrated assessment of the histopathological findings, bronchoalveolar lavage fluid SARS-CoV-2 PCR results, and the clinical course, antiviral and corticosteroid therapies were administered, followed by an improvement in the clinical course. This case suggests that cryobiopsy-based histopathology, integrated with the virological findings and clinical course, may provide complementary information for treatment selection in this patient population.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 14,
  "authors": [
    {
      "name": "Jun Hayashi"
    },
    {
      "name": "Tatsuya Nagai"
    },
    {
      "name": "Kurumi Seki"
    },
    {
      "name": "Masanori Toho"
    },
    {
      "name": "Yuki Sato"
    },
    {
      "name": "Hiroki Kawakami"
    },
    {
      "name": "Soichiro Yamaji"
    },
    {
      "name": "Hikaru Ito"
    },
    {
      "name": "Ayumu Otsuki"
    },
    {
      "name": "Hiroyuki Ito"
    },
    {
      "name": "Ryosuke Osawa"
    },
    {
      "name": "Junya Fukuoka"
    },
    {
      "name": "Kosei Matsue"
    },
    {
      "name": "Kei Nakashima"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ew49p30s7fh22.bib",
  "cited_by": 0,
  "doi": "10.2169/internalmedicine.7725-26",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7725-26/_article",
  "id": "ew49p30s7fh22",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7725-26/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "2725|COVID-19 Clinical Research Studies"
    ]
  ],
  "openalex": "W7224123053",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7725-26/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-29",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/ew49p30s7fh22.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:21:08Z",
      "native_id": "10.2169/internalmedicine.7725-26",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7725-26/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|COVID-19 Clinical Research Studies",
      "subfield": "infectious-disease"
    }
  ],
  "title": "A Case of Recurrent COVID-19 Pneumonia Following Rituximab Therapy: Treatment Informed by a Serial Transbronchial Lung Cryobiopsy, BALF SARS-CoV-2 PCR, and the Clinical Course",
  "title_text": "A Case of Recurrent COVID-19 Pneumonia Following Rituximab Therapy: Treatment Informed by a Serial Transbronchial Lung Cryobiopsy, BALF SARS-CoV-2 PCR, and the Clinical Course",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:21:08Z",
  "url": "https://research.draconitic.com/paper/ew49p30s7fh22",
  "venue": "Internal Medicine",
  "versions": []
}