{
  "abstract": "Objective: to execute a meta-synthesis grounded in third-order interpretations to critically deconstruct the distal determinants and social oppression forces driving problematic youth alcohol consumption in Latin America. This study analyzes a curated documentary corpus of 18 studies encompassing 21 countries indexed between 2015 and 2020, aiming to transcend dominant individualistic and Eurocentric reductionism in contemporary literature. Methods: a critical secondary analysis was developed using a third-order interpretive framework. The secondary corpus was derived from a prior systematic review conducted under the PRISMA statement. From an initial screening of n = 16,921 records (Google Scholar, Redalyc, SciELO), a strict analytical sample of 18 empirical investigations was selected (aggregate sample of N = 5,253 adolescents). Qualitative data were processed using structured thematic content analysis and axial coding within a personal, familial, and macrostructural relational model. Result: epistemological re-analysis identified five latent macrostructural dimensions operating asymmetrically across geographical regions: (1) socioeconomic inequality, (2) traditional consumption norms, (3) public health infrastructure deficiencies, (4) localized historical traumas, and (5) systemic violence. Furthermore, findings demonstrate that conventional scientific literature systematically omits these macrostructural determinants within direct empirical research designs. Conclusions: the findings elucidate a mechanism of social determination wherein economic macrostructures exert top-down oppressive violence, severely constraining micro-familial systems. These forces generate unsustainable pressure driving alcohol consumption and subsequent molecular damage as an adaptive somatic response that modulates gene expression in reaction to biopolitical traps. For social health research, these outcomes underscore the urgent need for an epistemic paradigm shift toward public policies targeting structural environmental interventions.\n\nKeywords: biopolitics, youth alcoholism, third-order secondary analysis, social determinants of health, macrostructural approach, epistemic violence.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 1,
  "authors": [
    {
      "name": "Carlos Fernando Pantoja Muñoz"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ewnf5e9qr8w6q.bib",
  "cited_by": 0,
  "doi": "10.31234/osf.io/amcbg_v1",
  "fulltext_url": null,
  "id": "ewnf5e9qr8w6q",
  "issns": [],
  "landing_url": "https://osf.io/preprints/psyarxiv/amcbg_v1/",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "bepress",
      "Engineering Psychology"
    ],
    [
      "bepress",
      "Neuroscience"
    ],
    [
      "bepress",
      "Psychiatry"
    ],
    [
      "bepress",
      "Social and Behavioral Sciences"
    ],
    [
      "openalex",
      "2713|Substance Abuse Treatment and Outcomes"
    ]
  ],
  "openalex": "W7221096657",
  "pdf_url": "https://osf.io/amcbg/download",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-07",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/ewnf5e9qr8w6q.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:38Z",
      "native_id": "amcbg",
      "source": "osf",
      "url": "https://osf.io/preprints/psyarxiv/amcbg_v1/"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "bepress:Neuroscience",
      "subfield": "neuroscience"
    },
    {
      "field": "medicine",
      "origin": "bepress:Psychiatry",
      "subfield": "psychiatry"
    }
  ],
  "title": "Macrostructural Determinants and Social Oppression Forces in Latin American Youth Alcoholism: A Three-Level Model Third-Order Secondary Analysis",
  "title_text": "Macrostructural Determinants and Social Oppression Forces in Latin American Youth Alcoholism: A Three-Level Model Third-Order Secondary Analysis",
  "type": "preprint",
  "updated_at": "2026-10-30T12:21:38Z",
  "url": "https://research.draconitic.com/paper/ewnf5e9qr8w6q",
  "venue": "PsyArXiv",
  "versions": []
}