{
  "abstract": "Vestibular migraine (VM) is a vestibular disorder characterized by recurrent episodes of vertigo, frequently accompanied by headache, nausea, and vomiting, which substantially reduce patients’ quality of life. The pathogenesis of VM remains incompletely understood. Current studies mainly focus on ion channel dysfunction, trigeminovascular mechanisms, and genetic susceptibility. Increasing evidence suggests that neuroinflammation and central sensitization play important roles in the onset and maintenance of VM. Microglia and astrocytes are key mediators of central sensitization, and their bidirectional communication represents an important component of neuroimmune interactions in the central nervous system. Based on recent studies, this review systematically summarizes the interactions and crosstalk between microglia and astrocytes in central sensitization, aiming to provide further insight into the pathophysiology of VM and to explore potential preventive and therapeutic strategies.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Encephalopathy, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine",
    "The First Clinical Medical College, Henan University of Traditional Chinese Medicine",
    "Henan Collaborative Innovation Center for Prevention and Treatment of Major Diseases with Integrated Traditional Chinese and Western Medicine",
    "Institute of Vertigo Diseases, Henan University of Traditional Chinese Medicine",
    "Henan Vertigo Disease Diagnosis and Treatment Center"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Tiancan Jin"
    },
    {
      "affs": [
        0,
        1,
        2,
        3,
        4
      ],
      "name": "Weitao Wang"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Jinghan Qin"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Yaru Liu"
    },
    {
      "affs": [
        0,
        1,
        2,
        3,
        4
      ],
      "name": "Xiaofei Fan"
    },
    {
      "affs": [
        0,
        1,
        2,
        3,
        4
      ],
      "name": "Daopei Zhang"
    },
    {
      "affs": [
        0,
        1,
        2,
        3,
        4
      ],
      "name": "Huailiang Zhang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/exdmfmrdzr90k.bib",
  "cited_by": 0,
  "doi": "10.3389/fnins.2026.1844932",
  "fulltext_url": "https://www.frontiersin.org/articles/10.3389/fnins.2026.1844932/full",
  "id": "exdmfmrdzr90k",
  "issns": [
    "1662-453X",
    "1662-4548"
  ],
  "landing_url": "https://www.frontiersin.org/articles/10.3389/fnins.2026.1844932/full",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC321-571"
    ],
    [
      "openalex",
      "2738|Migraine and Headache Studies"
    ]
  ],
  "openalex": "W7223365573",
  "pdf_url": "https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2026.1844932/pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-23",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/exdmfmrdzr90k.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:23Z",
      "native_id": "10.3389/fnins.2026.1844932",
      "source": "crossref",
      "url": "https://www.frontiersin.org/articles/10.3389/fnins.2026.1844932/full"
    },
    {
      "first_seen": "2026-10-30T13:43:59Z",
      "native_id": "b4f7f9c442844f108011690336893b4b",
      "source": "doaj",
      "url": "https://doi.org/10.3389/fnins.2026.1844932"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2738|Migraine and Headache Studies",
      "subfield": "psychiatry"
    }
  ],
  "title": "Research progress on the mechanism of microglia–astrocyte signal crosstalk in central sensitization of vestibular migraine",
  "title_text": "Research progress on the mechanism of microglia–astrocyte signal crosstalk in central sensitization of vestibular migraine",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:59Z",
  "url": "https://research.draconitic.com/paper/exdmfmrdzr90k",
  "venue": "Frontiers in Neuroscience",
  "versions": []
}