{
  "abstract": "Androgenetic alopecia (AGA) is the most common form of hair loss and can significantly impact quality of life. Emerging non-invasive treatments include laser-assisted delivery of biomimetic growth factor-based serums. The aim of the study was to evaluate the safety and efficacy of non-ablative fractional laser (NAFL)-assisted delivery, with or without adjunct red light therapy, in patients with AGA. In this pilot study, patients were randomly assigned to: (I) NAFL-assisted serum delivery plus red light therapy (triple), (II) NAFL-assisted serum delivery alone (dual), or (III) NAFL plus red light therapy without serum (EBD-only). Primary outcomes were hair density and thickness. Secondary outcomes included patient satisfaction, tolerability, and adverse events. Hair density increased in all groups, with greater improvement in the triple (25.6 ± 7.0 %) and dual (22.7 ± 3.4 %) groups compared to EBD-only (4.9 ± 9.2 %). Hair thickness improved in both serum groups but not in the EBD-only group. Clinical outcomes were similar between triple and dual treatments, though satisfaction was higher with triple therapy. No severe adverse events occurred. Preliminary evidence suggests that NAFL-assisted delivery of biomimetic growth factors is a safe and effective non-invasive treatment for AGA.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. l.nguyen@uke.de.",
    "Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Lynhda Nguyen",
      "orcid": "0000-0002-1258-6390"
    },
    {
      "affs": [
        1
      ],
      "name": "Stefan W Schneider"
    },
    {
      "affs": [
        1
      ],
      "name": "Katharina Herberger"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/ey885ksv2f9ff.bib",
  "cited_by": 0,
  "doi": "10.1007/s10103-026-05066-1",
  "fulltext_url": "https://europepmc.org/articles/PMC13690880",
  "id": "ey885ksv2f9ff",
  "issns": [
    "0268-8921",
    "1435-604X"
  ],
  "landing_url": "https://europepmc.org/article/MED/42911445",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2748|Hair Growth and Disorders"
    ]
  ],
  "openalex": "W7223171474",
  "pdf_url": "https://europepmc.org/articles/PMC13690880?pdf=render",
  "pmcid": "PMC13690880",
  "pmid": "42911445",
  "published": "2026-10-22",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/ey885ksv2f9ff.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:10Z",
      "native_id": "MED:42911445",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42911445"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2748|Hair Growth and Disorders",
      "subfield": "general"
    }
  ],
  "title": "Thulium laser-assisted delivery of growth factors for treating androgenetic alopecia - a randomized, controlled, clinical study.",
  "title_text": "Thulium laser-assisted delivery of growth factors for treating androgenetic alopecia - a randomized, controlled, clinical study.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:10Z",
  "url": "https://research.draconitic.com/paper/ey885ksv2f9ff",
  "venue": "Lasers in medical science",
  "versions": []
}