{
  "abstract": "Background\n\nFew reports of Pregnancy-related Acquired hemophilia A (AHA) manifested prenatally. Due to rarity, there are no definitive guidelines for the peripartum management of pregnant women with AHA and their newborns.Case presentation\n\nwe report a 30-year-old woman with relapsed AHA during pregnancy. She maintained partial remission with cyclosporin, underwent cesarean section with rFVIIa prophylaxis, and controlled postpartum bleeding. The newborn had transient FVIII inhibitors without bleeding.Conclusion\n\nBypassing agents effectively prevent postpartum hemorrhage in AHA. Close monitoring is necessary for newborns. We observed that immunosuppressive therapy administered during pregnancy and the postpartum period failed to eliminate FVIII inhibitors, highlighting contraception necessity for non-remission patients.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.",
    "Department of Nephrology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China."
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Hongyun Chen"
    },
    {
      "affs": [
        1
      ],
      "name": "Xiaochen Yu"
    },
    {
      "affs": [
        0
      ],
      "name": "Tienan Zhu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f08mxefv23f9w.bib",
  "cited_by": 0,
  "doi": "10.3389/fmed.2026.1963805",
  "fulltext_url": "https://europepmc.org/articles/PMC13747798",
  "id": "f08mxefv23f9w",
  "issns": [
    "2296-858X"
  ],
  "landing_url": "https://europepmc.org/article/MED/43010925",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2720|Hemophilia Treatment and Research"
    ]
  ],
  "openalex": "W7223950917",
  "pdf_url": "https://europepmc.org/articles/PMC13747798?pdf=render",
  "pmcid": "PMC13747798",
  "pmid": "43010925",
  "published": "2026-10-27",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/f08mxefv23f9w.ris",
  "sources": [
    {
      "first_seen": "2026-11-12T15:21:48Z",
      "native_id": "MED:43010925",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/43010925"
    },
    {
      "first_seen": "2026-11-13T12:25:15Z",
      "native_id": "PMC13747798",
      "source": "pmc",
      "url": "https://doi.org/10.3389/fmed.2026.1963805"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2720|Hemophilia Treatment and Research",
      "subfield": "general"
    }
  ],
  "title": "Case Report: Successful peripartum management of acquired hemophilia A relapse during pregnancy.",
  "title_text": "Case Report: Successful peripartum management of acquired hemophilia A relapse during pregnancy.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-13T12:25:15Z",
  "url": "https://research.draconitic.com/paper/f08mxefv23f9w",
  "venue": "Frontiers in medicine",
  "versions": []
}