{
  "abstract": "Although clinical trials showed outcomes improvement in MCL, their applicability to real-world practice remains limited. Using the prospective REALYSA registry (NCT03869619), we evaluated contemporary management, highlighting evolving practices and differences by age. Among 295 patients, 63% were ≥ 65 years, 48% had a high-risk MIPI score with Ki-67 ≥ 30% in 53% and aggressive morphology in 11%. Younger patients received high-dose cytarabine (93%) and ASCT (78%). Older patients were treated with bendamustine-rituximab (28%), R-CHOP (18%), and low-dose cytarabine (20%). Two-year event-free (EFS-2y) and overall (OS-2y) survivals were 80% and 89% in < 65y; 60% and 77% in ≥ 65y. Among 238 patients responders after induction,",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 34,
  "authors": [
    {
      "name": "Morgane Cheminant"
    },
    {
      "name": "Patrick Fogarty"
    },
    {
      "name": "Sylvain Carras"
    },
    {
      "name": "Clémentine Sarkozy"
    },
    {
      "name": "Cédric Rossi"
    },
    {
      "name": "Luc Fornecker"
    },
    {
      "name": "Bijou Fontanet"
    },
    {
      "name": "Adrien Chauchet"
    },
    {
      "name": "Sandra Leguyader‐peyrou"
    },
    {
      "name": "Laure Lebras"
    },
    {
      "name": "Lucie Oberic"
    },
    {
      "name": "Loïc Ysebaert"
    },
    {
      "name": "Ghandi Damaj"
    },
    {
      "name": "Gaelle Labouré"
    },
    {
      "name": "Ludovic Fouillet"
    },
    {
      "name": "Stéphanie Guidez"
    },
    {
      "name": "François Lemonnier"
    },
    {
      "name": "Krimo Bouabdallah"
    },
    {
      "name": "Thomas Gastinne"
    },
    {
      "name": "Nadine Morineau"
    },
    {
      "name": "Sandy Amorim"
    },
    {
      "name": "Fabrice Jardin"
    },
    {
      "name": "Julie Abraham"
    },
    {
      "name": "Roch Houot"
    },
    {
      "name": "Catherine Thieblemont"
    },
    {
      "name": "Franck Morschhauser"
    },
    {
      "name": "Rémy Gressin"
    },
    {
      "name": "Steven Le Gouill"
    },
    {
      "name": "Olivier Hermine"
    },
    {
      "name": "Fanny Cherblanc"
    },
    {
      "name": "Alain Monnereau"
    },
    {
      "name": "Aurélien Belot"
    },
    {
      "name": "Hervé Ghesquieres"
    },
    {
      "name": "Benoit Tessoulin"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f0qfbex9g3f5h.bib",
  "cited_by": 0,
  "doi": "10.1002/hon.70264",
  "fulltext_url": null,
  "id": "f0qfbex9g3f5h",
  "issns": [
    "0278-0232",
    "1099-1069"
  ],
  "landing_url": "https://u-bordeaux.hal.science/hal-05786298v1",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "hal",
      "1.sdv.spee"
    ],
    [
      "openalex",
      "2734|Lymphoma Diagnosis and Treatment"
    ]
  ],
  "openalex": "W7213897037",
  "pdf_url": "https://u-bordeaux.hal.science/hal-05786298/document",
  "pmcid": null,
  "pmid": "42767676",
  "published": "2026-10-08",
  "publisher": "Wiley",
  "ris": "https://research.draconitic.com/paper/f0qfbex9g3f5h.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:50Z",
      "native_id": "hal-05786298",
      "source": "hal",
      "url": "https://u-bordeaux.hal.science/hal-05786298v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    },
    {
      "field": "medicine",
      "origin": "hal:1.sdv.spee",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Contemporary Treatment and Survival Outcomes in Mantle Cell Lymphoma: A National Real‐World Analysis From REALYSA, a LYSA Cohort",
  "title_text": "Contemporary Treatment and Survival Outcomes in Mantle Cell Lymphoma: A National Real‐World Analysis From REALYSA, a LYSA Cohort",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:50Z",
  "url": "https://research.draconitic.com/paper/f0qfbex9g3f5h",
  "venue": "Hematological Oncology",
  "versions": []
}