{
  "abstract": "Background: Conventional radiographic assessment of postoperative lumbar alignment relies predominantly on Cobb angle measurements, which incompletely characterize global spinal morphology. We evaluated whether geometric morphometrics (GM) provides complementary quantitative information for assessing postoperative lumbar morphology after TLIF and decompression. Methods: Ninety-nine patients (TLIF n = 70; decompression n = 29) underwent landmark-based GM analysis of pre- and post-surgical lateral lumbar radiographs (48 landmarks, L1-S1). Because TLIF and decompression patients were imaged at markedly different postoperative intervals as a matter of routine clinical practice, the primary analyses tested whether each technique's own pre-to-post shape change, adjusted for baseline L1-S1 angle, log centroid size, sex, age, number of operated levels, and degenerative spondylolisthesis, was significant (sign-flip permutation test), along with lordosis change (paired t-test, unadjusted). Cobb analyses assessed global lumbar lordosis (L1-S1) and operated level(s). Results: TLIF showed a significant within-group reduction in global lumbar lordosis at early postoperative imaging (Δ = -3.75°, paired t-test p < 0.001) and a significant, systematic change in overall lumbar shape (sign-flip permutation p < 0.001); decompression showed no significant within-group change in global lordosis (Δ = +0.47°, p = 0.733) or overall shape (p = 0.31), but a small increase in segmental lordosis at the operated level(s) (Δ = +1.44°, p = 0.036) that was not robust to sensitivity analysis. Conclusions: In this retrospective cohort, TLIF was associated with reduced lumbar lordosis and a systematic shape change at early postoperative imaging, while decompression showed preserved global lordosis and a small gain in segmental lordosis at long-term imaging. GM provided a consistent quantitative framework, with strong correlation and level-dependent agreement against manual Cobb measurement, for characterizing these within-technique postoperative changes.",
  "abstract_shown": true,
  "affiliations": [
    "Spine Labs, St. George and Sutherland Clinical School, University of New South Wales, Sydney, NSW 2217, Australia.",
    "Department of Orthopedic Surgery, Tel Aviv Medical Center, Affiliated with Tel Aviv University, Tel Aviv 6997801, Israel.",
    "Levin Center for Surgical Innovation, Tel Aviv Medical Center, Affiliated with Tel Aviv University, Tel Aviv 6997801, Israel.",
    "Department of Anatomy and Anthropology, Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.",
    "Dan David Center for Human Evolution and Bio-History Research, Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.",
    "Department of Physical Education, Faculty of Sciences, Kibbutzim College of Education, Technology and the Arts, Tel Aviv 6250769, Israel.",
    "Centre for Orthopedics and Trauma Research, Adelaide Medical School, The University of Adelaide, Adelaide, SA 5005, Australia.",
    "Department of Neurosurgery, Spine Unit, Tel Aviv Medical Center, Affiliated with Tel Aviv University, Tel Aviv 6997801, Israel.",
    "Spine Service, Department of Orthopedic Surgery, St. George and Sutherland Clinical School, University of New South Wales, Sydney, NSW 2217, Australia.",
    "Spinal Unit, Discipline of Orthopedic Surgery, Royal Adelaide Hospital, Adelaide, SA 5000, Australia."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "affs": [
        0,
        1,
        2,
        3
      ],
      "name": "Amit Benady",
      "orcid": "0000-0003-3348-5000"
    },
    {
      "affs": [
        0
      ],
      "name": "Owen Zhou",
      "orcid": "0009-0006-1657-9573"
    },
    {
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        3,
        4,
        5
      ],
      "name": "Amit Hadad",
      "orcid": "0009-0006-8855-4930"
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    {
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        3,
        4
      ],
      "name": "Hila May"
    },
    {
      "affs": [
        6
      ],
      "name": "Ryan David Quarrington",
      "orcid": "0000-0002-0633-2482"
    },
    {
      "affs": [
        2
      ],
      "name": "Afek Ash",
      "orcid": "0009-0007-0743-8469"
    },
    {
      "affs": [
        0
      ],
      "name": "Stone Sima",
      "orcid": "0000-0002-1675-1496"
    },
    {
      "affs": [
        0
      ],
      "name": "Victor Chen",
      "orcid": "0009-0009-4461-4235"
    },
    {
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        1,
        7
      ],
      "name": "Morsi Khashan",
      "orcid": "0000-0001-8557-879X"
    },
    {
      "affs": [
        0,
        8,
        9
      ],
      "name": "Ashish Diwan",
      "orcid": "0000-0003-1037-8421"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f16q2vzxe45mj.bib",
  "cited_by": 0,
  "doi": "10.3390/diagnostics16193177",
  "fulltext_url": "https://europepmc.org/articles/PMC13664590",
  "id": "f16q2vzxe45mj",
  "issns": [
    "2075-4418"
  ],
  "landing_url": "https://europepmc.org/article/MED/42882332",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2746|Scoliosis diagnosis and treatment"
    ]
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  "openalex": "W7214897213",
  "pdf_url": "https://europepmc.org/articles/PMC13664590?pdf=render",
  "pmcid": "PMC13664590",
  "pmid": "42882332",
  "published": "2026-09-30",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/f16q2vzxe45mj.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:16Z",
      "native_id": "MED:42882332",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42882332"
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Scoliosis diagnosis and treatment",
      "subfield": "surgery"
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  ],
  "title": "Quantitative Assessment of Postoperative Lumbar Morphology Using Geometric Morphometrics: Within-Subject Changes Following TLIF and Decompression.",
  "title_text": "Quantitative Assessment of Postoperative Lumbar Morphology Using Geometric Morphometrics: Within-Subject Changes Following TLIF and Decompression.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:16Z",
  "url": "https://research.draconitic.com/paper/f16q2vzxe45mj",
  "venue": "Diagnostics (Basel, Switzerland)",
  "versions": []
}