{
  "abstract": "Surgical sutures are temporary load-bearing biomaterials whose performance in the oral cavity may be altered by postoperative mouthrinses. Seven USP 4-0 suture materials were immersed in four commercial mouthrinses for 3, 7, 10, and 14 days in a balanced factorial design (n = 3 per condition), with artificial saliva as a time-matched reference. Maximum breaking force (Fmax), apparent wet-state mass change, and solution pH were evaluated, and Day 14 re-dried mass was determined in an additional cohort (n = 5). Fmax was significantly affected by material, mouthrinse, time, and all interaction terms (p < 0.001), with material showing the largest main effect (partial η² = 0.957). Mean Fmax decreased by 57.1% for PGA and 53.3% for PGLA between Days 3 and 14 when averaged across mouthrinses. PGLA also declined in artificial saliva (-49.1%), showing that temporal loss was not exclusive to mouthrinse exposure. Mean apparent wet-state mass change ranged from 85.1% for silk to 8.5% for nylon 66 and showed a weak pooled association with Fmax (r = -0.163, p = 0.086); suture-related pH shifts were small. Under static immersion, response was specific to the material-formulation pair and evolved with time. Continuous immersion without medium renewal or prior salivary conditioning does not reproduce intermittent clinical mouthrinse use.",
  "abstract_shown": true,
  "affiliations": [
    "Institute of Biomedical Engineering, Faculty of Mechanical Engineering, Bialystok University of Technology, Wiejska 45C, 15-351 Bialystok, Poland.",
    "Digital Dentistry Lab, Department of Dental and Maxillofacial Radiodiagnostics, Faculty of Medical Dentistry, Medical University of Lublin, 20-059 Lublin, Poland.",
    "Department of Computerization and Robotics of Production, Faculty of Mechanical Engineering, Lublin University of Technology, Nadbystrzycka 36, 20-618 Lublin, Poland."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Alicja Choszczyk"
    },
    {
      "affs": [
        0
      ],
      "name": "Anna Ciołko"
    },
    {
      "affs": [
        0
      ],
      "name": "Wiktoria Nowak"
    },
    {
      "affs": [
        1
      ],
      "name": "Leszek Szalewski",
      "orcid": "0000-0003-1688-4982"
    },
    {
      "affs": [
        2
      ],
      "name": "Ewelina Kosicka",
      "orcid": "0000-0001-5143-5184"
    },
    {
      "affs": [
        0
      ],
      "name": "Żaneta Anna Mierzejewska",
      "orcid": "0000-0002-8363-9090"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f1dbnhesvd2xs.bib",
  "cited_by": 0,
  "doi": "10.3390/bioengineering13101178",
  "fulltext_url": "https://europepmc.org/articles/PMC13701215",
  "id": "f1dbnhesvd2xs",
  "issns": [
    "2306-5354"
  ],
  "landing_url": "https://europepmc.org/article/MED/42939033",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2746|Surgical Sutures and Adhesives"
    ]
  ],
  "openalex": "W7221089989",
  "pdf_url": "https://europepmc.org/articles/PMC13701215?pdf=render",
  "pmcid": "PMC13701215",
  "pmid": "42939033",
  "published": "2026-10-09",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/f1dbnhesvd2xs.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:22:24Z",
      "native_id": "MED:42939033",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42939033"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Surgical Sutures and Adhesives",
      "subfield": "surgery"
    }
  ],
  "title": "Mechanical and Gravimetric Response of Surgical Suture Biomaterials to Commercial Mouthrinses During Static In Vitro Exposure.",
  "title_text": "Mechanical and Gravimetric Response of Surgical Suture Biomaterials to Commercial Mouthrinses During Static In Vitro Exposure.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:22:24Z",
  "url": "https://research.draconitic.com/paper/f1dbnhesvd2xs",
  "venue": "Bioengineering (Basel, Switzerland)",
  "versions": []
}