{
  "abstract": "Blood pressure (BP) control among hypertensive people remains inadequate. This study aims to assess BP goal achievement among people prescribed antihypertensives, to examine medication nonadherence, and to identify demographics associated with goal achievements and medication nonadherence in this population. This was a cross-sectional analysis of the Mitchelstown Cohort Study Rescreen data. Goal achievement was assessed in accordance with the 2013 European guidelines, the guidelines in place during data collection. A validated, self-reported 3-item medication nonadherence questionnaire was used, with a mean score ranging from 1 (Perfect Adherence) to 5 (Perfect Nonadherence). Nonadherence was defined as mean score > 1. Multiple imputation was used to impute missing data on covariates and outcomes. A sensitivity analysis was performed to assess the consistency of results by applying the 2024 European guideline recommendations. Multivariable logistic regression analysis was used to identify the factors associated with BP goal achievements and medication nonadherence. Antihypertensives were prescribed to 567 participants. Based on imputed data, 63.8% of these achieved 2013 BP goal. Mean medication nonadherence score was 1.6 (SE ± 0.06), with 34.8% participants being nonadherent. Having multiple antihypertensives pills was associated with lower likelihood of achieving BP goals. In the sensitivity analysis, 38.4% achieved 2024 BP goal and in multivariable analysis, being overweight or obese was associated with not achieving the 2024 goals. The study highlights the gap between guideline BP goals and achieving these goals in real world practice. Key patient and medication factors were identified that could guide efforts to improve BP goal achievement. Trial Registration: ClinicalTrials.gov identifier: NCT03191227.",
  "abstract_shown": true,
  "affiliations": [
    "Pharmaceutical Care Research Group School of Pharmacy University College Cork Cork Ireland ucc.ie.",
    "Clinical Pharmacy Department Faculty of Pharmacy Minia University Minia Egypt minia.edu.eg.",
    "School of Public Health University College Cork Cork Ireland ucc.ie.",
    "MRC Integrative Epidemiology Unit at the University of Bristol University of Bristol Bristol UK bristol.ac.uk.",
    "Population Health Sciences Bristol Medical School University of Bristol Bristol UK bristol.ac.uk.",
    "School of Medicine University College Cork Cork Ireland ucc.ie.",
    "Pharmacy Department Bon Secours Hospital Cork Ireland bonsecours.com."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Rehab Elhiny",
      "orcid": "0000-0003-2411-4603"
    },
    {
      "affs": [
        2,
        3,
        4
      ],
      "name": "Linda M O'Keeffe"
    },
    {
      "affs": [
        5
      ],
      "name": "Tarun Das",
      "orcid": "0009-0009-6634-0060"
    },
    {
      "affs": [
        0,
        6
      ],
      "name": "Edel Burton",
      "orcid": "0000-0002-5847-0174"
    },
    {
      "affs": [
        2
      ],
      "name": "Seán R Millar",
      "orcid": "0000-0003-4453-8446"
    },
    {
      "affs": [
        0
      ],
      "name": "Stephen Byrne",
      "orcid": "0000-0003-3141-7004"
    },
    {
      "affs": [
        0
      ],
      "name": "Maria Donovan",
      "orcid": "0000-0003-0555-7492"
    },
    {
      "affs": [
        0
      ],
      "name": "Margaret Bermingham",
      "orcid": "0000-0002-8692-1569"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f1sbeq780bh4q.bib",
  "cited_by": 0,
  "doi": "10.1155/ijhy/1613515",
  "fulltext_url": "https://europepmc.org/articles/PMC13743861",
  "id": "f1sbeq780bh4q",
  "issns": [
    "2090-0384",
    "2090-0392"
  ],
  "landing_url": "https://europepmc.org/article/MED/42999744",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2714|Medication Adherence and Compliance"
    ]
  ],
  "openalex": "W7225452388",
  "pdf_url": "https://europepmc.org/articles/PMC13743861?pdf=render",
  "pmcid": "PMC13743861",
  "pmid": "42999744",
  "published": "2026-11-06",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/f1sbeq780bh4q.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T15:20:34Z",
      "native_id": "MED:42999744",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42999744"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:2705|Blood Pressure and Hypertension Studies",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Prescribing, Medication Adherence, and Blood Pressure Goal Achievement Among Middle-to-Older Age Adults in a Primary Care Setting.",
  "title_text": "Prescribing, Medication Adherence, and Blood Pressure Goal Achievement Among Middle-to-Older Age Adults in a Primary Care Setting.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T15:20:34Z",
  "url": "https://research.draconitic.com/paper/f1sbeq780bh4q",
  "venue": "International journal of hypertension",
  "versions": []
}