{
  "abstract": "Purpose\n\nAtrial fibrillation (AF) is the most common arrhythmia in patients with hypertrophic cardiomyopathy (HCM). This study aimed to investigate the associations of P-wave dispersion (PD) and left atrial reservoir strain (LASr) with incident AF.Methods\n\nThis single-center retrospective cohort study included 165 consecutive patients with HCM who were diagnosed at Liaoning Provincial People's Hospital from January 2018 to January 2026. Independent predictors of incident AF were identified using multivariable Cox regression. Model performance was assessed using a nomogram, time-dependent receiver operating characteristic curves, calibration curves, and decision curve analysis.Results\n\nDuring a median follow-up of 1.79 years, 56 (33.9%) patients developed incident AF. PD (P=0.025) and LASr (P=0.028) were independently associated with incident AF. The combined PD + LASr model showed AUCs of 0.766, 0.764, and 0.823 at 1, 2, and 3 years, respectively. The model showed good calibration at 3 years and positive net benefit across clinically relevant threshold probabilities. Kaplan-Meier analysis showed a significantly higher cumulative incidence of AF in the high-risk group than in the low-risk group (log-rank P<0.001).Conclusion\n\nPD and LASr are independently associated with AF risk in patients with HCM, and their combination may improve AF risk assessment.",
  "abstract_shown": true,
  "affiliations": [
    "Internal Medicine, Dalian Medical University, Dalian, People's Republic of China.",
    "Department of Cardiovascular Medicine, Liaoning Provincial People's Hospital, Shenyang, People's Republic of China.",
    "Department of Ultrasound, Liaoning Provincial People's Hospital, Shenyang, People's Republic of China."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Li Yu"
    },
    {
      "affs": [
        0
      ],
      "name": "Yan Zhang"
    },
    {
      "affs": [
        2
      ],
      "name": "Dandan Sun"
    },
    {
      "affs": [
        1
      ],
      "name": "Aijie Hou"
    },
    {
      "affs": [
        1
      ],
      "name": "Fei Xia"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f245hxpdasz4p.bib",
  "cited_by": 0,
  "doi": "10.2147/ijgm.s646378",
  "fulltext_url": "https://europepmc.org/articles/PMC13726645",
  "id": "f245hxpdasz4p",
  "issns": [
    "1178-7074"
  ],
  "landing_url": "https://europepmc.org/article/MED/42974149",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Research"
    ],
    [
      "openalex",
      "2705|Atrial Fibrillation Management and Outcomes"
    ]
  ],
  "openalex": "W7224129786",
  "pdf_url": "https://europepmc.org/articles/PMC13726645?pdf=render",
  "pmcid": "PMC13726645",
  "pmid": "42974149",
  "published": "2026-10-29",
  "publisher": "Dove Press",
  "ris": "https://research.draconitic.com/paper/f245hxpdasz4p.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T15:20:47Z",
      "native_id": "MED:42974149",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42974149"
    },
    {
      "first_seen": "2026-11-05T12:22:56Z",
      "native_id": "PMC13726645",
      "source": "pmc",
      "url": "https://doi.org/10.2147/ijgm.s646378"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Atrial Fibrillation Management and Outcomes",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Predictive Value of P-Wave Dispersion Combined with Left Atrial Reservoir Strain for Incident Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy: A Retrospective Cohort Study.",
  "title_text": "Predictive Value of P-Wave Dispersion Combined with Left Atrial Reservoir Strain for Incident Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy: A Retrospective Cohort Study.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:22:33Z",
  "url": "https://research.draconitic.com/paper/f245hxpdasz4p",
  "venue": "International journal of general medicine",
  "versions": []
}