{
  "abstract": "Breast malignancies can be difficult to assess on conventional imaging, particularly in patients with heterogeneous or dense breast tissue. We report the case of a woman in her early 70s with a biopsy-confirmed right breast malignancy who underwent contrast-enhanced spectral CT with both standard MonoE40 reconstruction and a dedicated breast spectral CT protocol. The dedicated reconstruction improved visualization of the primary lesion, associated dermal changes, ipsilateral axillary nodal abnormalities, and tumor vascularity, while also providing additional iodine-based enhancement information. These reconstructions were generated from the same CT acquisition and therefore required no additional radiation exposure or image acquisition. Subsequent surgical pathology confirmed locally advanced breast carcinoma with skin and regional nodal involvement, providing correlation with several of the imaging abnormalities. This case demonstrates the technical feasibility and qualitative added imaging information of dedicated breast spectral CT reconstruction in the assessment of a known breast malignancy undergoing preoperative staging.",
  "abstract_shown": true,
  "affiliations": [
    "Radiology, Mermaid Beach Radiology, Gold Coast, AUS"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Ashton Padowitz"
    },
    {
      "affs": [
        0
      ],
      "name": "Zane Sherif"
    },
    {
      "affs": [
        0
      ],
      "name": "Kirralee Sherif"
    },
    {
      "affs": [
        0
      ],
      "name": "Amanda Winspear"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f25jr2g0xee0m.bib",
  "cited_by": 0,
  "doi": "10.7759/cureus.117243",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722411/?tool=EBI",
  "id": "f25jr2g0xee0m",
  "issns": [
    "2168-8184"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13722411",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Oncology"
    ],
    [
      "heading",
      "Radiology"
    ],
    [
      "openalex",
      "2204|Advanced X-ray and CT Imaging"
    ]
  ],
  "openalex": "W7214999767",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722411/pdf/?tool=EBI",
  "pmcid": "PMC13722411",
  "pmid": "42964918",
  "published": "2026-09-30",
  "publisher": "Cureus Inc.",
  "ris": "https://research.draconitic.com/paper/f25jr2g0xee0m.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:21:36Z",
      "native_id": "PMC:PMC13722411",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13722411"
    },
    {
      "first_seen": "2026-11-03T12:22:55Z",
      "native_id": "PMC13722411",
      "source": "pmc",
      "url": "https://doi.org/10.7759/cureus.117243"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "heading:Radiology",
      "subfield": "imaging"
    },
    {
      "field": "medicine",
      "origin": "heading:Oncology",
      "subfield": "oncology"
    }
  ],
  "title": "Comparing a Dedicated Breast Spectral CT Protocol With Standard MonoE40 Reconstruction for Breast Cancer Characterization and Opportunistic Assessment",
  "title_text": "Comparing a Dedicated Breast Spectral CT Protocol With Standard MonoE40 Reconstruction for Breast Cancer Characterization and Opportunistic Assessment",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:22:55Z",
  "url": "https://research.draconitic.com/paper/f25jr2g0xee0m",
  "venue": "Cureus",
  "versions": []
}