{
  "abstract": "A central theme in Jon Kaas’ research, celebrated in this issue, is the relationship between brain structure and function. As a tribute, we examine how certain neuroanatomical structures enable higher-order (higher arity) functions whose joint effects cannot be recovered from pairwise measurements. Specifically, we argue that neurons exploit coincident input detection to realize higher-order operations that cannot be derived by studying any of the pairwise combinations in isolation. Pairwise statistics can miss these irreducible higher order (more-than-pairwise) effects. We advocate for an extension of graph-based models to hypergraphs to formally capture and analyze these irreducible higher-order neural interactions. Based on several recent studies, we discuss both the applicability and benefits of higher order neural data analyses.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 1,
  "authors": [
    {
      "name": "Alexander Maier"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f3jn9fws90pmc.bib",
  "cited_by": 0,
  "doi": "10.31234/osf.io/hpvsa_v2",
  "fulltext_url": null,
  "id": "f3jn9fws90pmc",
  "issns": [],
  "landing_url": "https://osf.io/preprints/psyarxiv/hpvsa_v2/",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "bepress",
      "Neuroscience"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://osf.io/hpvsa/download",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-03",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/f3jn9fws90pmc.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:26:06Z",
      "native_id": "hpvsa",
      "source": "osf",
      "url": "https://osf.io/preprints/psyarxiv/hpvsa_v2/"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "bepress:Neuroscience",
      "subfield": "neuroscience"
    }
  ],
  "title": "Structure Guides Function: Beyond Pairwise Neural Interactions",
  "title_text": "Structure Guides Function: Beyond Pairwise Neural Interactions",
  "type": "preprint",
  "updated_at": "2026-10-30T12:26:06Z",
  "url": "https://research.draconitic.com/paper/f3jn9fws90pmc",
  "venue": "PsyArXiv",
  "versions": []
}