{
  "abstract": "Study design Prospective observational multicenter cohort study. Objectives To determine Minimal Clinically Important Difference (MCID) of AO Spine PROST (Patient Reported Outcome Spine Trauma) and conducting a long-term prospective validation. Methods Data were collected from a prospective observational international multicenter cohort study. Adults (18-65) with acute thoracolumbar (TL) burst fractures without neurologic deficits were enrolled, and followed for up to 2 years. Patients completed the AO Spine PROST, Oswestry Disability Index (ODI), EQ-5D, and Pain NRS. Characteristics were analyzed using descriptive statistics, MCID for PROST with distribution-based approach using the standard deviation (SD) of change in scores. Floor and ceiling effects were also evaluated. Internal consistency (Cronbach’s alpha, item-total correlation coefficient (ITCC) and pairwise Spearman correlation), construct validity (Pearson correlations (r s ) with ODI, EQ-5D, Pain NRS), and responsiveness (effect sizes (ES) and standardized response mean (SRM)) were assessed. Results Ninety-three patients were included. MCID for a moderate change (0.5*SD) in PROST score was 10.6. No floor or ceiling effects were observed. Internal consistency was high (Cronbach’s α = 0.9-1.0 and acceptable ITCC). PROST scores strongly correlated with ODI (rs = −0.67 to −0.89; P < .001), but correlations with EQ-5D were weak (r s = −0.29 to 0.05; P > .005), except at 1-year follow-up. No consistent pattern was found with Pain NRS. Responsiveness was very good (ES = 3.2, SRM = 3.1; P < .001). Conclusions The AO Spine PROST identified an MCID of 10.6 as indicative of a moderate clinically meaningful change. The instrument also showed strong internal consistency, construct validity, and excellent responsiveness in long-term follow-up.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "name": "Said Sadiqi MD, PhD"
    },
    {
      "name": "Charlotte Dandurand MD, MSc, FRCSC"
    },
    {
      "name": "Richard J. Bransford MD"
    },
    {
      "name": "Lorin M. Benneker MD"
    },
    {
      "name": "Andrei F. Joaquim MD, PhD"
    },
    {
      "name": "Ulrich Spiegl MD"
    },
    {
      "name": "Jin W. Tee BMedSci, MBBS, MD, FRACS"
    },
    {
      "name": "Alexander R. Vaccaro MD, PhD, MBA"
    },
    {
      "name": "F. Cumhur Oner MD, PhD"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f4akg6wa0h0ea.bib",
  "cited_by": 0,
  "doi": "10.1177/21925682261445019",
  "fulltext_url": "https://doi.org/10.1177/21925682261445019",
  "id": "f4akg6wa0h0ea",
  "issns": [
    "2192-5682",
    "2192-5690"
  ],
  "landing_url": "https://doi.org/10.1177/21925682261445019",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC925-935"
    ],
    [
      "lcc",
      "RD1-811"
    ],
    [
      "openalex",
      "2746|Spinal Fractures and Fixation Techniques"
    ]
  ],
  "openalex": "W7154833313",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-31",
  "publisher": "SAGE Publishing",
  "ris": "https://research.draconitic.com/paper/f4akg6wa0h0ea.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T14:22:18Z",
      "native_id": "03d1df33864d43b59612d52b3a4051bb",
      "source": "doaj",
      "url": "https://doi.org/10.1177/21925682261445019"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Spinal Fractures and Fixation Techniques",
      "subfield": "surgery"
    }
  ],
  "title": "Minimal Clinically Important Difference (MCID) and Long-Term Prospective Validation of the AO Spine PROST (Patient Reported Outcome Spine Trauma)",
  "title_text": "Minimal Clinically Important Difference (MCID) and Long-Term Prospective Validation of the AO Spine PROST (Patient Reported Outcome Spine Trauma)",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T14:22:18Z",
  "url": "https://research.draconitic.com/paper/f4akg6wa0h0ea",
  "venue": "Global Spine Journal",
  "versions": []
}