{
  "abstract": "Objectives\n\nInfective endocarditis (IE) remains associated with substantial morbidity and mortality, although data from Oman and the Gulf region are limited. We aimed to describe the epidemiology, clinical characteristics, microbiological profile, and in-hospital outcomes of definite IE in a tertiary care hospital in Oman.Methods\n\nWe conducted a retrospective cohort study of patients admitted between 2006 and 2016. Cases were identified from electronic medical records using the International Classification of Diseases, Tenth Revision, Clinical Modification code I33.0. The modified Duke criteria were applied retrospectively and only definite IE cases were included.Results\n\nAmong 172 screened patients, 130 (75.6%) met the criteria for definite IE. The mean age was 42.3 years, and the median symptom duration before diagnosis was 14 days. Native valve IE occurred in 113 (87.0%) patients and prosthetic valve IE occurred in 17 (13.0%). Staphylococcus species were the most commonly isolated pathogens (43.1%), among which Staphylococcus aureus accounted for 38.5%. In-hospital mortality was 31.5%, and mortality was lower in patients who underwent surgery than in those who did not (18.0% vs 40.0%; P = 0.011).Conclusion\n\nIn this Omani cohort, IE affected a relatively young population and was characterized by predominant S. aureus infection and high in-hospital mortality. These findings support context-specific empiric therapy, early echocardiographic evaluation, and timely surgical assessment.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Infectious Diseases, The Royal Hospital, Muscat, Oman.",
    "Department of Cardio-thoracic Surgery, The Royal Hospital, Muscat, Oman.",
    "Research Department, Oman Medical Specialty Board, Muscat, Oman.",
    "School of Medical Sciences, University of Manchester, Manchester, UK."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Nasma Abdullah Al Sakiti"
    },
    {
      "affs": [
        1
      ],
      "name": "Ala Al-Lawati"
    },
    {
      "affs": [
        2
      ],
      "name": "Sachin Jose"
    },
    {
      "affs": [
        3
      ],
      "name": "Kawther Al Bahrani"
    },
    {
      "affs": [
        0
      ],
      "name": "Faryal Khamis"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f4trr0va2ypgx.bib",
  "cited_by": 0,
  "doi": "10.1016/j.ijregi.2026.101033",
  "fulltext_url": "https://europepmc.org/articles/PMC13694845",
  "id": "f4trr0va2ypgx",
  "issns": [
    "2772-7076"
  ],
  "landing_url": "https://europepmc.org/article/MED/42926847",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2713|Infective Endocarditis Diagnosis and Management"
    ]
  ],
  "openalex": "W7216119828",
  "pdf_url": "https://europepmc.org/articles/PMC13694845?pdf=render",
  "pmcid": "PMC13694845",
  "pmid": "42926847",
  "published": "2026-10-02",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/f4trr0va2ypgx.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:18Z",
      "native_id": "MED:42926847",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42926847"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Infective Endocarditis Diagnosis and Management",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Epidemiology, clinical characteristics, and outcomes of infective endocarditis over a decade in a tertiary care hospital in Oman.",
  "title_text": "Epidemiology, clinical characteristics, and outcomes of infective endocarditis over a decade in a tertiary care hospital in Oman.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:18Z",
  "url": "https://research.draconitic.com/paper/f4trr0va2ypgx",
  "venue": "IJID regions",
  "versions": []
}