{
  "abstract": "二甲苯异构体及乙基苯由于分子组成相同、理化性质高度相似，其高效分离与痕量杂质检测长期以来是色谱分离领域的经典难题。金属有机骨架材料（MOFs）凭借高度有序且可精确调控的孔道结构、丰富可设计的孔内化学环境以及多样化的主客体相互作用机制，为解决C8芳香族异构体分离提供了新的材料体系与解决方案。MOFs的孔径尺寸、形状各向异性及孔壁官能团可在分子尺度上进行精准调控等优点，使其在分子筛分效应、π-π相互作用、范德华力及扩散动力学调控等方面展现出独特优势。本文系统综述了MOFs作为气相色谱固定相在C8芳香族异构体分离中的研究进展。首先，总结了C8芳香族异构体分离的基本理论基础，重点阐述了分子筛分、孔内相互作用及扩散动力学等机制在分离过程中的作用。鉴于MOF分离过程通常涉及多种机制的协同作用，本文重点选取并讨论了各类分离机理下具有代表性的典型研究案例。随后，从不同金属节点构筑的代表性MOF材料出发，系统分析了各种MOF色谱柱的分离结果。在此基础上，进一步综述了色谱柱内壁表面修饰方法及MOF色谱柱的构筑策略，讨论其对固定相分离效果的影响。最后，总结了近年来MOF固定相分离C8芳香族异构体的应用和发展趋势，并对其未来发展方向进行了展望。本文旨在为高性能MOF固定相的理性设计及其在复杂芳烃体系分离中的实际应用提供参考与启示。",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "name": "Xuhan ZHANG"
    },
    {
      "name": "Ming XU"
    },
    {
      "name": "Zhiyuan GU"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/f54npgxrf7ka1.bib",
  "cited_by": 0,
  "doi": "10.3724/sp.j.1123.2026.01036",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13729057/",
  "id": "f54npgxrf7ka1",
  "issns": [
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    "1872-2059"
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  "landing_url": "https://doi.org/10.3724/sp.j.1123.2026.01036",
  "language": "zh",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "O658"
    ],
    [
      "heading",
      "Reviews"
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    [
      "heading",
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    [
      "openalex",
      "1602|Analytical Chemistry and Chromatography"
    ]
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  "openalex": "W7225175453",
  "pdf_url": null,
  "pmcid": "PMC13729057",
  "pmid": "42973218",
  "published": "2026-11-07",
  "publisher": "Editorial Office of Chinese Journal of Chromatography",
  "ris": "https://research.draconitic.com/paper/f54npgxrf7ka1.ris",
  "sources": [
    {
      "first_seen": "2026-11-07T12:21:53Z",
      "native_id": "PMC13729057",
      "source": "pmc",
      "url": "https://doi.org/10.3724/sp.j.1123.2026.01036"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1602|Analytical Chemistry and Chromatography",
      "subfield": "analytical"
    }
  ],
  "title": "基于金属有机骨架固定相的C8芳香族异构体气相色谱分离研究进展",
  "title_text": "基于金属有机骨架固定相的C8芳香族异构体气相色谱分离研究进展",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:21:53Z",
  "url": "https://research.draconitic.com/paper/f54npgxrf7ka1",
  "venue": "Chinese Journal of Chromatography",
  "versions": []
}